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Table 1 The effect of TRPA1 antagonist 50 μg HC-030031 on cystometry parameters of inflammatory rats

From: Intrathecal administration of TRPA1 antagonists attenuate cyclophosphamide-induced cystitis in rats with hyper-reflexia micturition

      

Compliance (μl/mmHg)

N-VC (number)

  

BP (mmHg)

PT (mmHg)

MP (mmHg)

ICI (min)

 

No-treatment

13.11 ± 6.14

15.86 ± 6.25

24.33 ± 8.78

3.92 ± 1.41

139.10 ± 49.47

0.25 ± 0.5

Control

Treatment

11.24 ± 3.11

14.25 ± 3.44

21.54 ± 5.34

4.08 ± 1.32

159.15 ± 76.02

0

 

Recovery

11.17 ± 3.08

14.86 ± 3.48

21.53 ± 5.14

3.90 ± 0.74

146.46 ± 65.47

0

 

No-treatment

10.10 ± 5.74

11.83 ± 6.16

19.11 ± 8.01

2.28 ± 0.51

124.78 ± 49.52

3.25 ± 0.5

Cystitis

Treatment

7.70 ± 3.29

9.83 ± 3.05

17.29 ± 6.87

4.14 ± 1.05*

98.12 ± 25.15

1.25 ± 0.50**

 

Recovery

7.39 ± 3.75

10.05 ± 4.25

15.72 ± 7.00

3.10 ± 0.31

136.80 ± 42.92

1.25 ± 0.50**

  1. Results were expressed as mean ± standard error. The “*” or “**” represented the difference was significant between the treatment or recovery and no-treatment in cystometry parameters. *P < 0.05, ** P < 0.01