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Table 2 Pathological Features of Entire Cohort

From: Multi-disciplinary surgical approach to the management of patients with renal cell carcinoma with venous tumor thrombus: 15 year experience and lessons learned

Characteristic

Total (%)

Level I (%)

Level II (%)

Level III (%)

Level IV (%)

P value

 

146 (100)

77 (53)

48 (33)

12 (8)

9 (6)

 

T stage

     

<0.001

 T3a

75 (51)

75 (97)

0

0

0

 

 T3b

51 (35)

0

40 (83)

11 (92)

0

 

 T3c

8 (6)

0

0

0

8 (89)

 

 T4

12 (8)

2 (3)

8 (17)

1 (8)

1 (11)

 

Grade

     

0.015

 1

1 (1)

0

0

1 (8)

0

 

 2

24 (16)

17 (22)

5 (10)

1 (8)

1 (11)

 

 3

86 (59)

39 (51)

32 (67)

10 (84)

5 (56)

 

 4

35 (24)

21 (27)

1 (23)

0

3 (33)

 

Path tumor size (cm)

10.2 ± 4.5

9.2 ± 4.3

11.7 ± 4.6

10 ± 2.9

12 ± 6.3

0.02

(2–25)

(2–23)

(3.5-25)

(5.5-15)

(5–22)

 

Metastasis

     

0.3

 Absent

104 (71)

56 (73)

31 (65)

11 (92)

6 (67)

 

 Present

42 (29)

21 (27)

17 (35)

1 (8)

3 (33)

 

LN

     

0.01

 N0

69 (47)

30 (39)

29 (60)

5 (42)

5 (56)

 

 Nx

48 (33)

36 (47)

6 (13)

4 (33)

2 (22)

 

 N+

29 (20)

11 (14)

13 (27)

3 (25)

2 (22)

 

Sarcomatoid Differentiation

     

0.3

 Absent

127 (87)

68 (88)

39 (81)

12 (100)

8 (89)

 

 Present

19 (13)

9 (1)

9 (19)

0

1 (11)

 

Adrenal Involvement

     

0.08

 Absent

128 (88)

72 (94)

38 (79)

11 (92)

7 (78)

 Present

18 (12)

5 (6)

10 (21)

1 (8)

2 (22)

Tumor Necrosis

     

0.4

 Absent

52 (36)

32 (42)

15 (31)

3 (25)

2 (22)

 Present

94 (64)

45 (58)

33 (69)

9 (75)

7 (78)

Fat Invasion

     

0.3

 Absent

28 (19)

18 (23)

7 (15)

3 (25)

0 (0)

 Present

118 (81)

59 (77)

41 (85)

9 (75)

9 (100)

Histological Subtype

     

0.7

 Non clear cell

11 (8)

5 (6)

5 (10)

1 (8)

0 (0)

 Clear cell

135 (92)

72 (94)

43 (90)

11 (92)

9 (100)