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Table 2 This table shows the diagnostic performance of RTE and PCA3 score with cut-off 35 for the group of any PCa, for the combined group of intermediate-and high-risk PCa, and for high-risk PCa

From: A positive Real-Time Elastography (RTE) combined with a Prostate Cancer Gene 3 (PCA3) score above 35 convey a high probability of intermediate- or high-risk prostate cancer in patient admitted for primary prostate biopsy

 

Parameter

Sensitivity

Specificity

NPV

PPV

Any PCa

RTE

74 %

39 %

54 %

61 %

 

PCA3

64 %

78 %

66 %

80 %

 

Combination

91 %

26 %

70 %

62 %

IR and HR PCa

RTE

86 %

43 %

82 %

51 %

 

PCA3

71 %

66 %

78 %

58 %

 

Combination

96 %

24 %

90 %

55 %

HR PCa

RTE

88 %

35 %

95 %

18 %

 

PCA3

82 %

57 %

95 %

23 %

 

Combination

100 %

19 %

100 %

16 %

  1. Abbreviations: PCa prostate cancer, IR intermediate-risk, HR high-risk, RTE real-time elastography, PCA3 prostate cancer gene 3, NPV negative predictive value, PPV positive predictive value