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Table 3 Logistic regression analyses for predicting high and intermediate risk prostate cancer (n = 124)

From: A positive Real-Time Elastography (RTE) combined with a Prostate Cancer Gene 3 (PCA3) score above 35 convey a high probability of intermediate- or high-risk prostate cancer in patient admitted for primary prostate biopsy

 

Simple

Multiple

 

Unadjusted

Fully adjusted

Final model

Variables

OR

95 % CI

p-value**

OR

95 % CI

p-value**

OR

95 % CI

p-value**

Age (cont. in years)

1.04

(0.98,1.10)

0.188

1.04

(0.96, 1.13)

0.287

   

PSA (cont. in ng/ml)

1.18

(1.08, 1.29)

<0.001

1.19

(1.07, 1.34)

0.001

1.18

(1.03, 1.14)

0.001

Pvol. (cont. in ml)

0.98

(0.96, 0.99)

0.003

0.97

(0.95, 0.99)

0.005

1.04

(1.04, 1.07)

0.009

Positive RTE (Y/N)

4.46

(1.78, 11.22)

0.001

2.73

(0.96, 7.79)

0.052

2.56

(0.91, 7.23)

0.068

PCA3 (>35 vs. <35)

5.00

(2.28, 10.95)

<0.001

3.31

(1.27, 8.63)

0.013

4.12

(1.71, 9.91)

0.001

  1. Abbreviations: RTE: real-time elastography, Cont continuous, Y/N yes/no, OR odds ratio, CI confidence interval, Pvol prostate volume
  2. **p-value by the use of the Likelihood Ratio test