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Table 2 Changes in the values of the subjective and objective symptoms in each group of elderly male patients with overactive bladder

From: The efficacy of mirabegron additional therapy for lower urinary tract symptoms after treatment with α1-adrenergic receptor blocker monotherapy: prospective analysis of elderly men

 

Young-old group (N = 22)

Old-old group (N = 28)

 

0 W

12 W

P Value

0 W

12 W

P Value

OABSS

      

 Q1 Daytime frequency

1.1 ± 0.7

1.4 ± 0.8

0.307

1.1 ± 0.8

1.4 ± 0.5

0.148

 Q2 Nighttime frequency

2.1 ± 1.0

1.5 ± 0.9

0.034

2.0 ± 0.8

1.5 ± 0.6

0.005

 Q3 Urgency

2.7 ± 1.1

1.2 ± 1.1

< 0.001

2.2 ± 0.4

1.3 ± 0.6

< 0.001

 Q4 Urgency incontinence

0.9 ± 1.3

0.3 ± 0.6

0.021

0.2 ± 0.4

0.3 ± 0.4

0.686

 Total score

6.5 ± 2.7

4.4 ± 1.6

0.004

5.6 ± 1.3

4.2 ± 1.2

< 0.001

IPSS

      

 Q1 Incomplete emptying

1.2 ± 1.4

1.2 ± 1.3

1.000

1.2 ± 1.0

1.4 ± 1.2

0.093

 Q2 Frequency

3.0 ± 1.1

2.0 ± 1.0

0.001

3.1 ± 0.7

2.1 ± 0.9

< 0.001

 Q3 Intermittency

1.4 ± 1.3

1.2 ± 1.3

0.205

1.0 ± 1.0

1.1 ± 1.2

0.529

 Q4 Urgency

2.8 ± 0.8

1.7 ± 0.9

< 0.001

2.6 ± 0.8

1.5 ± 1.0

< 0.001

 Q5 Weak stream

2.2 ± 1.1

2.0 ± 1.2

0.142

2.2 ± 1.0

2.3 ± 1.0

0.689

 Q6 Straining

2.0 ± 1.5

1.7 ± 1.4

0.110

1.3 ± 0.8

1.4 ± 0.9

0.529

 Q7 Nocturia

3.3 ± 0.8

2.3 ± 1.4

0.001

2.9 ± 0.8

1.9 ± 0.9

< 0.001

 Total score

16.0 ± 5.1

12.0 ± 5.3

< 0.001

14.5 ± 3.3

11.7 ± 4.1

< 0.001

Storage symptoms (Q2 + Q4 + Q7)

9.1 ± 1.9

6.0 ± 2.5

< 0.001

8.7 ± 5.6

5.6 ± 2.0

< 0.001

 Voiding symptoms (Q1 + Q3 + Q5 + Q6)

6.8 ± 4.4

6.0 ± 4.4

0.029

5.8 ± 2.5

6.1 ± 3.0

0.102

 QOL score

4.3 ± 1.0

3.5 ± 1.4

0.006

4.1 ± 0.8

3.2 ± 1.0

< 0.001

Urodynamic study

      

 VV (mL)

141.0 ± 78.1

169.5 ± 74.0

0.012

134.4 ± 49.2

142.0 ± 53.4

0.133

 Qmax (mL/s)

9.1 ± 3.0

9.9 ± 2.7

0.159

9.1 ± 2.2

12.0 ± 12.4

0.116

 PVR (mL)

27.4 ± 41.8

22.1 ± 22.7

0.879

26.5 ± 17.3

30.4 ± 25.9

0.190

  1. OABSS overactive bladder symptom score, IPSS international prostate symptom score, w week, VV voided volume, Qmax maximum flow rate, PVR post-void residual urine