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Table 1 General characteristics of men with BPH using finasteride or dutasteride

From: Rates of prostate surgery and acute urinary retention for benign prostatic hyperplasia in men treated with dutasteride or finasteride

 

Dutasteride

Finasteride

monotherapy

& alpha-blocker

monotherapy

& alpha-blocker

N = 3,147

N = 8,675

N = 2,264

N = 3,517

n (%)

n (%)

n (%)

n (%)

Age at cohort entry

 50–54 years

150 (5)

330 (4)

172 (8)

148 (4)

 55–59 years

320 (10)

860 (10)

255 (11)

371 (11)

 60–64 years

468 (15)

1,541 (18)

341 (15)

577 (16)

 65–79 years

1,659 (53)

4,681 (54)

1,101 (49)

1,847 (53)

 80–84 years

330 (10)

848 (10)

246 (11)

378 (11)

 85–89 years

169 (5)

348 (4)

101 (4)

151 (4)

  ≥ 90

51 (2)

67 (1)

48 (2)

45 (1)

 Mean (±SD)

70 ± 10

70 ± 9

69 ± 10

70 ± 9

Prescriber of first 5-ARI

 Urologist

1,705 (54)

5,053 (58)

653 (29)

1,412 (40)

 GP

1,063 (34)

2,242 (26)

1,275 (56)

1,546 (44)

 Other

379 (12)

1,380 (16)

336 (15)

559 (16)

Prior use of urological care

 Yes

2,055 (65)

6,164 (71)

943 (42)

1,946 (55)

History of bladder or kidney stones

 Yes

50 (2)

148 (2)

16 (1)

48 (1)

Comorbidities

    

 Hypertension

1,653 (53)

4,444 (51)

1,116 (49)

1,771 (50)

 Hypercholesterolemia

1,060 (34)

2,948 (34)

662 (29)

1,094 (31)

 Diabetes type I

42 (1)

113 (1)

50 (2)

73 (2)

 Diabetes type II

322 (10)

930 (11)

209 (9)

372 (11)

 Parkinson’s disease

42 (1)

148 (2)

41 (2)

50 (1)

 Multiple sclerosis

1 (<0.5)

1 (<0.5)

0 (0)

2 (<0.5)

Chronic disease score

 0–3

1,402 (45)

3,987 (46)

1,137 (50)

1,634 (46)

 4–7

939 (30)

2,516 (29)

619 (27)

1,017 (29)

  ≥ 8

806 (26)

2,172 (25)

508 (22)

866 (25)

 Mean (±SD)

5 ± 4

5 ± 4

4 ± 4

5 ± 4

Adherence (MPR 5-ARI) (%)

 Mean (±SD)

84 ± 13

85 ± 13

81 ± 14

84 ± 13

Database follow-up after cohort entry date

  ≥ 1 year

2,264 (100)

3,517 (100)

3,147 (100)

8,675 (100)

  ≥ 2 years

1,906 (84)

2,975 (85)

2,361 (75)

6,395 (74)

  ≥ 3 years

1,596 (70)

2,463 (70)

1,700 (54)

4,526 (52)

  ≥ 4 years

1,291 (57)

1,991 (57)

1,115 (35)

2,972 (34)

  ≥ 5 years

970 (43)

1,490 (42)

618 (20)

1,715 (20)

  1. SD standard deviation, IQR interquartile range, MPR medication possession rate