Fig. 3
From: miR-199a-5p suppresses human bladder cancer cell metastasis by targeting CCR7
miR-199a-5p directly targeted the 3′UTR of CCR7 and inhibited the expression of MMP-9 and EMT-related proteins in T24 cells. a Predicted binding sequences of miR-199a-5p in the 3′UTR of CCR7. b Luciferase reporter assays in T24 cells. c The gene expression of CCR7 was detected by qRT-PCR in T24 cells. d The protein expression of CCR7, E-cadherin, Vimentin and MMP-9 were determined by western blot in T24 cells. Data are expressed as means ± SD of three independent experiments. * P < 0.05 compared with the negative control group