Table 2 Summary of extracted clinical data
Study | Type | Population | Study duration | Hydrophilic Arm (H) | Non-hydrophilic arm (NH) | UTIs | Haematuria (number of patients or episodes) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Patients | Mean age | Catheter brand/type | Patients | Mean age | Catheter brand/type | ||||||
Single-use standard catheters | |||||||||||
Cardenas 2009 [17] * | RCT | Neurological | 12 months | 22 (77% males) | 42.3 ± 10.4 | LoFric/NA | 23 (52% males) | 40.1 ± 9.3 | NA/NA | Mean number of UTIs: H: 1.18 ± 1.3 NH: 1.00 ± 1.0 (p = NS) Subjects who had at least one UTI: H: 12 (54%) NH: 14 (61%) (p = NS) | NA |
Cardenas 2011 [18] * | RCT | Neurological | 6 months | 105 (79% males) | 37.2 ± 14.4 | Coloplast/Speedicath | 114 (82% males) | 35.1 ± 13.2 | Coloplast/Conveen | Mean number of UTIs per month (according to clinical definition): Full study period H: 0.479 NH: 0.478 (p = NS) Institutional period H: 0.539 NH: 0.682 (p = 0.038) Mean number of UTIs per month (according to strict definition): Full study period H: 0.198 NH: 0.218 (p = NS) Institutional period H: 0.189 NH: 0.295 (p = 0.022) Subjects who had at least 1 UTI (estimated from curves): H: 69 out of 91 patients NH: 85 out of 97 patients | H: 14 NH: 6 (p < 0.0001) |
De Ridder 2005 [19] * | RCT | Neurological | 12 months | 61 (100% males) | 37. 5 ± 14.6 | Coloplast/Speedicath | 62 (100% males) | 36.7 ± 14.6 | Coloplast/Conveen | Subjects who had at least one UTI: H: 39 (64%) NH: 51 (82%) (p = 0.02) | H: 38 out of 55 patients NH: 32 out of 59 patients (p = NS) |
Massa 2009 [29] | RCT | Neurological | 12 months | 25 | NA | LoFric/NA | 26 | NA | NA/NA | Number of UTIs in the first 3 months: H: 17 NH: 12 (p = NS) | NA |
Sarica 2010 [30] * | Crossover | Neurological | 18 weeks | 10 (100% males) | 37.04 ± 11.86 | Teleflex/Rusch Flocath | 10 (100% males) | 37.04 ± 11.86 | NA/NA | Subjects who had at least one UTI: H: 1 NH: 4 (p = NS) | NA |
Wyndaele 2000 [31] * | Crossover | Neurological | 2 years | 39 (100% males) | 45 ± 15 | Coloplast/UroCath Gel | 39 (100% males) | 45 ± 15 | NA/NA | NA | H: 10 NH: 9 (p = NS) |
Reused standard catheters | |||||||||||
Pachler 1999 [33] * | Crossover | Non-neurological | 3 weeks | 32 (100% males) | 71.3 years (range 50–87) | LoFric/NA | 32 (100% males) | 71.3 years (range 50–87) | Mentor/NA | Subjects who had at least one UTI: H: 2 NH: 2 (p = NS) | H: 2 NH: 2 (p = NS) |
Sutherland 1996 [34] * | RCT | Neurological or non-neurological | 8 weeks | 17 (100% males) | 11.7 ± 3.8 | LoFric/NA | 16 (100% males) | 12.1 ± 5.7 | Mentor/NA | Subjects who had at least 1 UTI (bacteriuria and fever): H: one out of 16 patients NH: one out of 14 patients (p = NS) | H: six out of 16 patients NH: 11 out of 14 patients |
Vapnek 2003 [32] | RCT | Neurological | 12 months | 30 (100% males) | 39.8 ± 12.9 | LoFric/NA | 31 (100% males) | 39.6 ± 16.0 | NA/NA | Mean number of UTIs per month per patient: H: 0.13 ± 0.18 NH: 0.14 ± 0.21 | NA |