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Table 2 Results of univariate ordinal logistic regression testing for association of predictor variables with regret post-biopsy: odds ratios (OR) with 95% confidence intervals (CI) and p- values

From: Do men regret prostate biopsy: Results from the PiCTure study

 

Frequency

Univariate Analysis

 

n (%)

OR (95% CI)a

p-value*

Total

295 (100.0)

  

Socio-demographic variables

Age at questionnaire completion

  <65 years

174 (59.0)

1.00

 

  ≥65 years

118 (40.0)

0.89 (0.56, 1.42)

0.64

 Missing

3 (1.0)

  

Marital status

 Married/ partnership

229 (77..6)

1.00

 

 Other

65 (22.0)

0.99 (0.57, 1.71)

0.96

 Missing

1 (0.3)

  

Highest education level completed

 Primary/secondary school

211 (71.5)

1.00

 

 Third level

77 (26.1)

0.67 (0.40, 1.14)

0.14

 Missing

7 (2.4)

  

Employment status

 Working

114 (38.6)

1.00

 

 Retired

117 (39.7)

0.72 (0.43, 1.22)

 

 Other

55 (18.6)

1.17 (0.62, 2.19)

0.27

 Missing

9 (3.1)

  

Health anxiety

 Low

100 (33.9)

1.00

 

 Intermediate

132 (44.8)

1.80 (1.05, 3.10)

 

 High

63 (21.4)

3.18 (1.68, 6.02)

0.001

 Missing

0 (0.0)

  

Clinical variables

Given choice of first PSA

 Yes

215 (72.9)

1.00

 

 No

57 (19.3)

0.86 (0.48, 1.53)

0.60

 Missing

23 (7.8)

  

Pre-biopsy symptoms

 Incontinence

   

 None/mild

222 (75.3)

1.00

 

 Moderate/severe

45 (15.3)

1.12 (0.59, 2.11)

0.73

 Missing

28 (9.5)

  

Erectile dysfunction

 None/mild

213 (72.2)

1.00

 

 Moderate/ severe

65 (22.0)

1.08 (0.62, 1.89)

0.77

 Missing

17 (5.8)

  

Symptoms at time of PSA test

   

 Asymptomatic

166 (56.3)

1.00

 

 Symptomatic

106 (35.9)

1.34 (0.83, 2.17)

0.23

 Other/Missing

23 (7.8)

  

Enough information pre-biopsy

 Yes received enough

238 (80.7)

1.00

 

 Yes but would have liked more

24 (8.1)

1.84 (0.81, 4.19)

 

 No but did not want/need any

5 (1.7)

2.84 (0.47, 17.27)

 

 No but would have liked some

12 (4.1)

1.10 (0.34, 3.54)

0.36

 Missing

16 (5.4)

  

Biopsy result

 Negative

106 (35.9)

1.00

 

 Positive

97 (32.9)

1.45 (0.84, 2.51)

 

 Don’t know

92 (31.2)

1.34 (0.76, 2.35)

0.38

Expectations of side-effects

 Same as expected

108 (36..6)

1.00

 

 Worse than expected

41 (13.9)

1.97 (0.98, 3.96)

 

 Not as bad as expected

54 (18.3)

1.39 (0.72, 2.68)

 

 Did not have side-effects

83 (28.1)

1.08 (0.60, 1.93)

0.24

 Missing

9 (3.1)

  

Number of biopsies

 One

209 (70.9)

1.00

 

 More than one

72 (24.4)

0.62 (0.36, 1.07)

0.08

 Missing

14 (4.8)

  

Physical Side-effects from biopsy

Any side-effect b

 Yes

263 (89.2)

1.00

 

 No

32 (10.9)

0.88 (0.42, 1.84)

0.74

 Missing

0 (0.0)

  
  1. *p-values obtained from the likelihood ratio test
  2. aThe OR for ordinal logistic regression shows the likelihood of having an increased level of the outcome variable (regret) within each category of the predictor variable compared to a reference category in the predictor variable
  3. bFever, bleeding, pain, erectile dysfunction and urinary retention