Fig. 4

LOX immunoreactivity score by HIF-1α positivity in epithelial cells. Patients with positive HIF-1α expression are prone to higher LOX IRS. HIF-1α, hypoxia inducible factor – 1 alpha; LOX, lysyl oxidase. IRS, immunoreactivity score. Mann–Whitney non-parametric test was used to calculate differences between positive and negative HIF-1α expression