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Table 2 Association of the genetic polymorphisms in HIF1A +1772 C > T and CA9 + 201 A > G with HIF-1α and CAIX immunoreactivity in prostatic epithelial cells

From: Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer

 

Recessive model (HIF1A and CA9)

 

HIF-1α expression

CC

TT/CT

P a

Negative

28 (0.76)

9 (0.24)

 

Positive

10 (0.77)

3 (0.23)

0.928

<50%

32 (0.74)

11 (0.26)

 

≥50%

6 (0.86)

1 (0.14)

0.516

CAIX expression

GG

GA/AA

 

Negative

9 (0.75)

20 (0.69)

 

Positive

3 (0.25)

9 (0.31)

0.699

  1. a Fisher exact test