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Table 1 The clinical and pathological features of patients

From: Transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume: 103 cases requiring repeat prostate biopsy

Variables

Median (range) or n (%)

Total

n = 103

Prostate cancer

n = 53

No prostate cancer

n = 50

P

Age, years

69 (37–83)

71 (48–79)

67 (37–83)

<0.01

No. of TRUS biopsies

1 (1–5)

1 (1–5)

1 (1–3)

0.48

No. of cores obtained pre-TRUSBs

12 (8–13)

12 (8–13)

12 (8–12)

0.89

PSA, ng/mL

9.2 (1.9–107)

10.7 (1.9–42.1)

8.8 (4.5–107)

0.33

Free-PSA ratio, %

15.3 (1.3–67.1)

12.9 (4.3–25.7)

16.9 (1.3–67.1)

0.04

PSA density, ng/mL/mL

0.26 (0.06–1.9)

0.33 (0.06–1.3)

0.23 (0.07–1.9)

0.02

PSA velocity, ng/mL/year

1.12 (−29–129)

1.39 (−29–26)

0.75 (−8.8–129)

0.66

DRE, abnormal findings

17 (16.5)

13 (24.5)

4 (8.0)

0.03

TRUS, abnormal findings

21 (20.3)

14 (26.4)

7 (14.0)

0.13

MRI, abnormal findings (n = 14)

9/14 (64.2)

6/9 (66.7)

3/5 (60.0)

0.93

Prostate volume, mL

34.7 (18–76.7)

30.8 (18–65.1)

39.4 (20.1–76.7)

<0.01

HGPIN on previous biopsy

13 (12.6)

7 (13.2)

6 (12.0)

0.88

ASAP on previous biopsy

10 (9.7)

8 (15.1)

2 (4.0)

0.06

No of cores obtained by TTSB

37 (18–75)

32 (22–66)

41.5 (18–75)

<0.01

Core/volume, cores/mL

1.05 (0.80–1.77)

1.05 (0.80–1.31)

1.05 (0.80–1.77)

0.07

  1. Mann-Whitney U test, Chi-squared test
  2. TRUS transrectal ultrasound, PSA prostate specific antigen, DRE digital rectal examination, HGPIN high grade prostatic intraepithelial neoplasia, ASAP atypical small acinar proliferation, TTSB transperineal template-guided sasturation biopsy, Core/volume number of cores per unit volume of prostate