Table 3 Univariate and multivariate analysis of factors that predict positive for prostate cancer
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Categories | Odds ratio (95% CI) | P | Odds ratio (95% CI) | P |
Age | ||||
≤ 70.3 | (Ref) | (Ref) | ||
> 70.3 | 3.80 (1.68–8.61) | <0.01 | 4.96 (1.67–14.7) | <0.01 |
No. of TURSBs | ||||
≤ 1 | (Ref) | |||
> 1 | 0.70 (0.31–1.60) | 0.78 | ||
No. cores obtained by pre-TURSBs | ||||
≤ 10 | (Ref) | |||
> 10 | 1.01 (0.87–1.16) | 0.91 | ||
PSA | ||||
≤ 9.3 | (Ref) | |||
> 9.3 | 1.85 (0.83–4.07) | 0.12 | ||
Free PSA ratio | ||||
≤ 13.6 | (Ref) | (Ref) | ||
> 13.6 | 0.33 (0.14–0.78) | 0.01 | 0.45 (0.13–1.60) | 0.22 |
PSA density | ||||
≤ 0.27 | (Ref) | (Ref) | ||
> 0.27 | 2.69 (1.20–6.01) | 0.02 | 2.03 (0.468–6.01) | 0.20 |
PSA velocity | ||||
≤ 1.2 | (Ref) | |||
> 1.2 | 1.91 (0.86–4.25) | 0.11 | ||
DRE | ||||
Benign | (Ref) | (Ref) | ||
Suspicious | 3.73 (1.12–12.3) | 0.03 | 2.87 (0.72–11.5) | 0.13 |
TRUS | ||||
Benign | (Ref) | |||
Suspicious | 2.20 (0.81–6.03) | 0.12 | ||
Prostate volume | ||||
≤ 34.1 | (Ref) | (Ref) | ||
> 34.1 | 0.24 (0.11–0.55) | <0.01 | 0.28 (0.09–0.90) | 0.03 |
HGPIN on previous biopsy | ||||
Absent | (Ref) | |||
Present | 1.11 (0.35–3.58) | 0.85 | ||
ASAP on previous biopsy | ||||
Absent | (Ref) | |||
Present | 4.23 (0.86–21.2) | 0.08 | ||
Core/volume | ||||
≤ 1.05 | (Ref) | |||
> 1.05 | 3.28 (0.41–24.5) | 0.26 | ||