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Table 2 - Comparison of the susceptibility to commonly used first-line antibiotics and chemotherapeutics of the common susceptible isolates with that of isolates producing β-lactamase (ESBL or AmpC)

From: The susceptibility to fosfomycin of Gram-negative bacteria isolates from urinary tract infection in the Czech Republic: data from a unicentric study

Antibiotic

Escherichia coli (n = 1578)

Escherichia coli beta lactamase positivea (n = 125)

Klebsiella pneumoniae (n = 359)

Klebsiella pneumoniae beta lactamase positivea (n = 284)

Enterobacter species (n = 186)

Enterobacter species beta lactamase positivea (n = 75)

S%

I%

R%

S%

I%

R%

S%

I%

R%

S%

I%

R%

S%

I%

R%

S%

I%

R%

Fosfomycin

97.4

0.8

1.8

92.0

1.6

6.4

85.8

5.6

8.6

73.6

14.8

11.6

86.1

4.8

9.1

74.7

9.3

16.0

Ampicilin

50.0

0.0

50.0

0.0

0.0

100.0

0.0

0.0

100.0

0.0

0.0

100.0

0.0

0.0

100.0

0.0

0.0

100.0

Ampicilin-sulbactam

82.4

0.0

17.6

0.0

0.0

100.0

78.3

0.0

21.7

0.0

0.0

100.0

0.0

0.0

100.0

0.0

0.0

100.0

Cefuroxime

97.7

0.0

2.3

0.0

0.0

100.0

92.8

0.0

7.2

0.0

0.0

100.0

0.0

0.0

100.0

0.0

0.0

100.0

Ciprofloxacin

80.6

0.3

19.1

16.0

0.0

84.0

84.5

1.2

14.3

12.0

0.0

88.0

88.7

1.1

10.2

49.3

8.0

42.7

Co-trimoxazole

71.0

0.4

28.6

28.0

0.0

72.0

80.5

0.3

19.2

10.2

0.4

89.4

84.9

0.0

15.1

38.6

2.7

58.7

Nitrofurantoin

97.1

0.0

2.9

89.6

0.0

10.4

76.6

0.0

23.4

50.0

0.0

50.0

65.1

0.0

34.9

65.3

0.0

34.7

  1. abeta lactamase positive means bacterial isolates producing ESBL or AmpC beta lactamase