Transperineal ultrasound-guided prostate biopsy is safe even when patients are on combination antiplatelet and/or anticoagulation therapy

Table 6 Multivariate analysis to predict the risk factors for bleeding events

	Variable	N	Hazard ratio	95% CI	p value
Age	< 70	294	-	-
Age	≥ 70	265	0.931	0.657–1.319	0.687
PSA, ng/ml	< 6.0	158	-	-
	6.0–9.9	214	0.839	0.551–1.277	0.413
	≥ 10	187	0.696	0.450–1.076	0.103
Number of biopsy cores	< 16	204	-	-
Number of biopsy cores	≥ 16	355	0.974	0.683–1.389	0.883
Prostate volume, cm³	< 45.0	278	-	-
Prostate volume, cm³	≥ 45.0	281	1.135	0.805–1.600	0.470
No. of AP/AC agents	0	420	-	-
	1	105	1.339	0.863–2.076	0.193
	≥ 2	34	2.230	1.028–4.839	0.042

PSA Prostate specific antigen, AP Antiplatelet, AC Anticoagulant, CI Confidence interval

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