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Fig. 3 | BMC Urology

Fig. 3

From: Role of calcifying nanoparticles in the development of testicular microlithiasis in vivo

Fig. 3

Testis ultrastructural observations by TEM. a Normal cell population typically localized in the seminiferous tubules and no morphological changes were observed in the testis of control mice. b and c At 2 weeks, many globoid or racket-shaped particles in cytoplasm were observed under TEM in group B and C (yellow arrows). In addition, microcalcification surrounded by globoid human NPs within the seminiferous tubules increasingly occurred in affected tubules in group C (white arrows). d At four weeks, microcalcification surrounded by cellular debris within the seminiferous tubules displayed the characteristic features of testicular microlithiasis in group C only (Fig. 3d; red arrow)

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