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Table 3 Candidate genes which function as transmembrane ion transporter, Ca ion binder or diuretic hormone that may play a role in crystal formation

From: A Drosophila genetic model of nephrolithiasis: transcriptional changes in response to diet induced stone formation

 

Gene name

GO Molecular function

Log FC

Sodium oxalate group

nervana 3

plasma membrane Na:K- exchanging ATPase activity

−1.29

Excitatory amino acid transporter 1

Na: dicarboxylate symporter activity; Na:glutamate symporter activity

−0.93

CG7912

High affinity Sulfate transmembrane transporter

−1.25

Crystallin

Ca ion binding

0.945

Ethylene Glycol group

CG3036

Na: phosphate symporter activity

1.24

CG5404

high affinity sulfate transmembrane transporter

1.2

Dh44

Diuretic hormone activity

2.38