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Table 3 miRNA expression and prognostic factors of ccRCC

From: Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics

  miR-199a miR-100 miR-99a miR-99b miR-126 miR-29a miR-29b
Low (n = 18) 60.12(104.18) 0.51(1.34) 17.89(34.38) 22.01(37.5) 2.10(4.1) 19.25(28.23) 3.94(7.35)
Intermediate (n = 29) 59.99(159.22) 5.62(25.37) 22.18 (49.15) 13.07(31.1) 0.96(2.9) 10.90(28.49) 2.72(2.89)
High n = 9 48.64(85.19) 0.77(1.75) 44.44(75.01) 65.13(159.) 0.37(0.3) 7.05(9.72) 5.30(2.91)
P 0.65b 0.63b 0.50b 0.17b 0.29b 0.57b 0.47b
Size ≥7 cm (n = 30) 61.13(91.26) 5.69(26.31) 19.77(39.93) 22.79(42.3) 1.57(3.6) 13.80(24.88) 3.48(6.21)
Size <7 cm (n = 26) 55.80(166.90) 0.90(2.77) 27.68(56.40) 23.59(84.3) 1.02(2.1) 12.62(28.97) 3.29(2.90)
P 0.88a 0.36a 0.57a 0.96a 0.49a 0.88a 0.12a
MVI absent (n = 44) 63.00(145.83) 3.90(20.87) 15.77(34.2) 17.73(35.1) 1.55(3.2) 15.24(29.69) 3.19(5.13)
MVI present (n = 12) 43.28(73.27) 0.88(1.80) 51.97(76.99) 43.48(127.) 0.36(0.3) 5.37(7.45) 4.30(3.50)
P 0.65a 0.63a 0.05a 0.72a 0,43a 0.33a 0.54a
Fuhrman’s Grade I e II (n = 32) 39.95(87.23) 0.49(1.32) 23.61(45.13) 17.40(31.4) 1.92(3.7) 19.08(34.41) 3.63(6.04)
Fuhrman’s Grade III e IV (n = 24) 79.35(169.23) 6.35(26.88) 23.28(52.73) 29.41(88.9) 0.55(1.2) 5.70(7.80) 3.11(3.06)
p 0.28a 0.33a 0.98a 0.51a 0.03 a 0.10a 0,71a
pT1–2 (n = 26) 50.88(82.18) 6.36(27.40) 22.79(42.04) 23.35(43.8) 1.19(2.7) 14.85(25.19) 3.86(6.32)
pT3–4 (n = 30) 65.37(166.50) 0.69(2.59) 24.12(53.93) 23.01(81.1) 1.41(3.1) 11.84(28.52) 2.96(3.03)
P 0.69a 0.28a 0.92a 0.98a 0.78a 0.71a 0.51a
Metastasis Absent (n = 48) 49.76(84.62) 3.46(19.85) 19.01(39.85) 25.78(69.88) 1.17(2.54) 12.23(26.81) 3.61(418.33)
Metastasis Present (n = 8) 107.88(286.69) 1.89(4.94) 48.92(81.75) 6.41(6.35) 2.20(5.18) 18.95(28.74) 2.24(3.24)
p 0.25a 0.83a 0.12a 0.47a 0.39a 0.57a 0.46a
  1. aMann-Whitney test b Anova b Kruskall-Wallis Test
  2. significant p-value are highlighted in bold