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Table 6 Univariate and multivariate analyses of upgrading predictions for targeted versus systematic biopsies

From: A prospective study of magnetic resonance imaging and ultrasonography (MRI/US)-fusion targeted biopsy and concurrent systematic transperineal biopsy with the average of 18-cores to detect clinically significant prostate cancer

 

Univariate analysis

Multivariate analysis

OR

95% CI

p-value

OR

95% CI

p-value

PI-RADS v2 category

5

1.14

0.37–3.45

0.8215

4

4.24

1.40–12.8

0.0064a

4.33

1.46–14.6

0.0077a

PSAD >0.17 (yes vs. no)

2.71

0.74–9.91

0.1179

DRE (yes vs. no)

0.79

0.24–2.57

0.6910

Number of biopsies per PV ≥0.5 (yes vs. no)

1.77

0.62–5.11

0.2836

Age < 65 years (yes vs. no)

3.64

1.28–10.4

0.0111a

3.73

1.28–11.4

0.0165a

Repeat biopsy (yes vs. no)

1.05

0.28–3.92

0.9417

  1. OR odds ratio, CI confidence interval, PSAD prostate-specific antigen density, DRE digital rectal examination, PV prostate volume
  2. astatistically significant