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Table 2 Stereological data of right and left kidneys of pigs subjected to sham surgery or to left renal ischemia with or without mannitol administration

From: Mannitol reduces nephron loss after warm renal ischemia in a porcine model

 

Sham

Ischemia

Mannitol

 

Right

Left

p-value

Right

Left

p-value

Right

Left

p-value

Kidney weight (g)

56.8 ± 4.9

58.2 ± 8.5

0.52

59.2 ± 10.9

55.5 ± 11.0

0.008

58.5 ± 10.4

55.4 ± 8.5

0.06

Kidney volume (ml)

54.4 ± 4.1

55.2 ± 7.7

0.70

56.6 ± 9.8

53.0 ± 10.5

0.007

55.4 ± 9.8

52.5 ± 8.1

0.09

Cortical-medullar ratio (%)

71.6 ± 2.3

70.4 ± 4.1

0.32

71.8 ± 2.4

70.1 ± 2.2

0.04

71.4 ± 4.0

71.9 ± 3.3

0.72

Cortical volume (ml)

38.9 ± 3.3

38.9 ± 6.5

0.98

40.6 ± 7.4

37.2 ± 7.9

0.002

39.3 ± 5.9

37.8 ± 6.2

0.17

Vv [glom] (%)

3.79 ± 0.5

3.72 ± 0.5

0.68

3.59 ± 0.4

3.08 ± 0.9

0.16

4.06 ± 0.9

3.72 ± 0.8

0.37

VWGV (105 μm3)

13.4 ± 1.6

12.7 ± 1.1

0.25

12.5 ± 2.4

12.4 ± 1.2

0.94

14.1 ± 3.9

14.3 ± 3.9

0.86

Glomeruli (millions)

1.10 ± 0.1

1.14 ± 0.2

0.68

1.18 ± 0.2

0.89 ± 0.2

0.04

1.18 ± 0.4

0.99 ± 0.2

0.18

  1. Data expressed as mean ± S.D.