Study | Type of study | Gender | Patients (n) | Follow-up median (month) | Median age (year) | Node status (overall)/ LND or NLND | Extent of LND | Tumor location | Pathologic tumor stage | Tumor grade | Outcome |
---|---|---|---|---|---|---|---|---|---|---|---|
Kondo T et al 2014 [31] | Prospective | Male 112 Female 54 | 166 | 23.7 | 72.4 | pN0 69 pNx 86 pN+ 11 | Renal pelvis tumor: LN from the renal hilar to the inferior mesenteric artery. Tumor of upper 2/3 ureter: LN from the renal hilar to the aortic bifurcation. Tumor of lower 1/3 ureter: the ipsilateral pelvic LN | Renal pelvis 90 Ureter 76 | ≤pT1 62 pT2 27 pT3 72 pT4 5 | Low 71 High 95 | CSS |
Ouzzane A et al 2013 [16] | Retrospective | Male 484 Female 228 | 714 | 27.0 | 70.0 | pN0 204 pNx 460 pN+ 50 | NA | Renal pelvis 388 Pelvis+ureter 90 Multifocal 236 | pTa/Tis 209 pT1 168 pT2 74 pT3 224 pT4 39 | G1 71 G2 244 G3 399 | CSS, RFS |
Mason RJ et al. 2012 [15] | Retrospective | Male 654 Female 375 | 1029 | 19.8 | 68.6 | pN0 199 pNx 753 pN+ 77 | NA | Renal pelvis 538 Pelvis+ureter 213 Ureter 250 | pTa/Tis 108 pT1 463 pT2 160 pT3 244 pT4 54 | Low 340 High 689 | CSS, RFS |
Burger M et al 2011 [30] | Retrospective | Male 542 Female 243 | 785 | 34.0 | 68.0 | pN0 136 pNx 595 pN+ 54 | Hilar & regional LN adjacent to ipsilateral great vessel | NA | pTa 165 pTis 10 pT1 196 pT2 148 pT3 222 pT4 44 | G1 100 G2 226 G3 459 | CSS, RFS |
Abe T et al 2010 [29] | Retrospective | Male 195 Female 98 | 293 | NA | 69.2 | pN0 130 pNx 141 pN+ 22 | Tumor of renal pelvis tumor & upper 2/3 ureter: Hilar & regional LN adjacent to ipsilateral great vessel Lower ureteral tumor: ipsilateral pelvic LN | Renal pelvis 157 Pelvis+ureter 24 Ureter 112 | pTa/Tis 53 pT1 66 pT2 56 pT3 101 pT4 17 | Low 185 High 108 | RFS |
Lughezzani et al 2010 [14] | Retrospective | Male 1666 Female 1158 | 2824 | 43.0 | 72.0 | pN0 1835 pNx 747 pN+ 242 | NA | Renal pelvis 1913 Ureter 911 | pT1 867 pT2 500 pT3 584 pT4 873 | G1 156 G2 935 G3 1234 G4 499 | CSS |
Roscigno M et al 2009 [28] | Retrospective | NA | 1130 | 45.0 | 69.1 | pN0 412 pNx 578 pN+ 140 | Renal pelvis and proximally ureteral tumor: LN from the renal hilar to the inferior mesenteric artery Mid and lower ureteral tumors: LN from the renal hilar to the bifurcation of the common iliac artery and ipsilateral pelvic LN | NA | pT1 317 pT2 269 pT3–4544 | Low 291 High 839 | CSS |
Kondo T et al. 2007 [27] | Retrospective | Male 113 Female 56 | 169 | 37.3 | 67.5 | LND 81 NLND 88 | Renal pelvis tumor: LN from the renal hilar to the inferior mesenteric artery Tumor of upper 2/3 ureter: LN from the renal hilar to the aortic bifurcation Tumor of lower 1/3 ureter: ipsilateral pelvic LN | Renal pelvis 100 Upper ureter 9 Midureter 20 Lower ureter 40 | ≤pT1 45 pT2 34 pT3 79 pT4 9 | NA | CSS |
Secin FP et al. 2007 [26] | Retrospective | Male 166 Female 86 | 252 | 37.2 | 69.0 | pN0 105 pNx 119 pN+ 28 | NA | NA | pTa 71 pTis 12 pT1 46 pT2 35 pT3 72 pT4 8 | G1 64 G2 38 G3 143 | CSS |
Brausi MA et al 2007 [25] | Retrospective | Male 59 Female 23 | 82 | 64.7 | LND 67.8 NLND 67.1 | LND 40 NLND 42 | Renal pelvis and upper ureteral tumor: LN from the renal hilar to the inferior mesenteric artery Mid ureteral tumors: LN from the renal hilar to the bifurcation of the common iliac artery Lower ureteral tumor: ipsilateral pelvic LN | Renal pelvis 47 Pelvis+ureter 7 Ureter 28 | pT2 38 pT3 36 pT4 8 | G2 44 G3 38 | CSS |
Miyake H et al.. 1998 [24] | Retrospective | Male 53 Female 19 | 72 | 49 | LND 64 NLND 67 | LND 35 NLND 38 | Renal pelvis and upper ureteral tumor: LN from the renal hilar to the inferior mesenteric artery Mid ureteral tumor: LN from the renal hilar to the bifurcation of the common iliac artery Lower ureteral tumor: ipsilateral pelvic LN | Renal pelvis 40 Pelvis+ureter 3 Ureter 29 | pTa 11 pT1 25 pT2 18 pT3 14 pT4 4 | G1 12 G2 33 G3 37 | CSS |