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Table 3 Univariate and multivariate analysis for prostate cancer detection in all patients

From: Cancer detection rate of prebiopsy MRI with subsequent systematic and targeted biopsy are superior to non-targeting systematic biopsy without MRI in biopsy naïve patients: a retrospective cohort study

 

Univariate analysis

Multivariate analysis

 

N

HR

95% CI

p-value

HR

95% CI

p-value

Age

≤  65

189

(−)

(−)

0.101

66–70

147

1.166

0.755–1.801

0.488

   

> 70

160

1.836

1.119–2.812

0.005

   

PSA

≤  5.0

89

5.01–7.50

219

1.194

0.721–1.978

0.491

1.346

0.767–2.363

0.300

7.51–10

97

1.949

1.085–3.499

0.026

2.620

1.342–5.115

0.005

>  10.0

91

2.712

1.484–4.955

0.001

3.947

1.995–7.806

< 0.001

Prostate volume

≤  25.0

176

25.1–35.0

147

0.361

0.228–0.571

< 0.001

0.336

0.205–0.551

< 0.001

>  35.0

173

0.135

0.084–0.217

< 0.001

0.112

0.073–0.204

< 0.001

MRI

No

281

Yes

215

1.712

1.197–2.450

0.003

1.749

1.160–2.636

0.008

DRE

Negative

411

Positive

85

4.193

2.467–7.126

< 0.001

3.068

1.704–5.526

< 0.001

TRUS

Negative

435

-

-

-

(−)

(−)

0.154

Positive

61

2.500

1.418–4.407

0.002