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Table 2 Association of EGFR Expression with clinicopathologic features of Urothelial carcinoma

From: Prognostic significance of epidermal growth factor receptor (EGFR) over expression in urothelial carcinoma of urinary bladder

 

EFGR Expression n (%)

P-Value

No Expression (n = 74)

Low EFGR Expression (n = 19)

High EFGR expression (n = 33)

Total (n = 126)

Gender

 Male

54(73)

14(73.7)

23(69.7)

91(72.2)

0.930

 Female

20(27)

5(26.3)

10(30.3)

35(27.8)

Age Groupa

 ≤ 25 years

1(1.4)

0(0)

0(0)

0(0)

0.263

 26–50 years

21(28.4)

2(10.5)

2(10.5)

5(15.2)

 > 50 years

52(70.3)

17(89.5)

17(89.5)

28(84.8)

Specimen Type a

 Transurethral resection

72(97.3)

19(100)

30(90.9)

121(96)

0.209

 Radical Cystectomy

2(2.7)

0(0)

3(9.1)

5(4)

Tumor Grade

 Low Grade

48(64.9)

9(47.4)

8(24.2)

65(51.6)

0.000

 High Grade

26(35.1)

10(52.6)

25(75.8)

61(48.4)

Lamina Propria Invasion

 Present

15(20.3)

3(15.8)

17(51.5)

35(27.8)

0.002

 Absent

59(79.7)

16(84.2)

16(48.5)

91(72.2)

Deep Muscle Invasion a

 Present

9(12.2)

1(5.3)

12(36.4)

22(17.5)

0.012

 Absent

38(51.4)

12(63.2)

9(27.3)

59(46.8)

 Can’t Assessed

27(36.5)

6(31.6)

12(36.4)

45(35.7)

Recurrence (n = 58) a

 Yes

15(40.5)

0(0)

10(66.7)

25(43.1)

0.017

 No

22(59.5)

6(100)

5(33.3)

33(56.9)

Survival Status (n = 58) a

 Alive

32(86.5)

6(100)

11(73.3)

49(84.5)

0.398

 Expired

5(13.5)

0(0)

4(26.7)

9(15.5)

  1. Chi-Square test applied
  2. aFisher Exact test applied
  3. P-Value≤0.05, considerd as significant