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Table 2 Baseline characteristics of chemotherapy-naïve mCRPC patients in the STRIVE and TERRAIN trials

From: Number-needed-to-treat analysis of clinical progression in patients with metastatic castration-resistant prostate cancer in the STRIVE and TERRAIN trials

Baseline characteristics

STRIVE

TERRAIN

Enzalutamide

(n = 128)

Bicalutamide

(n = 129)

Enzalutamide

(n = 184)

Bicalutamide

(n = 191)

Age, years

 Median

71

72

71

71

 Range

46–87

50–90

50–96

48–91

Race, n (%)

 Black or African-American

14 (10.9)

15 (11.6)

8 (4.3)

10 (5.2)

 White

107 (83.6)

111 (86.0)

172 (93.4)

176 (92.1)

 Other

7 (5.5)

3 (2.3)

4 (2.2)

5 (2.6)

Baseline weight, kg

 Median

91.6

88.3

88.2

86.8

 Range

58.5–166.6

52.7–181.8

57.0–184.1

56.0–143.5

Body mass index, kg/m2

 Median

30

29

28

28

 Range

20–49

16–62

18–51

18–44

ECOG performance status, n (%)

 0

92 (71.9)

92 (71.3)

130 (70.7)

146 (76.4)

 1

36 (28.1)

37 (28.7)

54 (29.3)

45 (23.6)

Serum PSA, μg/L

 Median

15.1

18.3

21

22

 Range

0.0–1499.7

0.2–2849.7

0.6–5000

0.1–4681

  1. ECOG Eastern Cooperative Oncology Group, mCRPC metastatic castration-resistant prostate cancer, PSA prostate-specific antigen