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Table 2 A: Optimal multivariable logit models predicting 90-day mortality and B: Optimal multivariable proportional hazard models predicting non-bladder cancer (competing) mortality with 95% confidence intervals and p values in all patients, patients aged 80 years or older and patients younger than 80 years including the variables age, Charlson score and ASA classification

From: Predicting 90-day and long-term mortality in octogenarians undergoing radical cystectomy

 

Whole sample

< 80 years

80+ years

A: Endpoint 90-day mortality

Parameter

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

 Age (continuous variable, per year)

1.05 (1.01-1.09)

0.0106

n. s.*

1.24 (1.01-1.51)

0.0422

 Charlson-Score (continuous variable, per point)

1.16 (1.02- 1.31)

0.0197

1.22 (1.07-1.39)

0.0029

n. s.**

 ASA classes 3-4 (versus classes 1-2)

6.95 (2.80-17.2)

< 0.0001

9.28 (3.11-27.8)

< 0.0001

n. s.**

B: Endpoint non-bladder-cancer (competing) mortality

Parameter

HR (95% CI)

p

HR (95% CI)

p

HR (95% CI)

p

 Age (continuous variable, per year)

1.04 (1.02-1.05)

< 0.0001

1.04 (1.02-1.06)

< 0.0001

n. s.***

 Charlson-Score (continuous variable, per point)

1.17 (1.02-1.24)

< 0.0001

1.18 (1.11-1.26)

< 0.0001

n. s.***

 ASA classes 3-4 (versus classes 1-2)

1.59 (1.21-2.08)

0.0008

1.67 (1.25-2.25)

0.0006

n. s.***

  1. ASA American Society Association physical status classification [11]; OR Odds ratio; HR Hazard ratio; CI Confidence interval; n. s. Not significant. *Full model: age: OR 1.04 (0.99-1.09), p = 0.14, Charlson score: OR 1.21 (1.06-1.38), p = 0.0050, ASA classes 3-4: OR 8.48 (2.83-25.40), p = 0.0001. **Full model: age: OR 1.18 (0.97-1.48), p = 0.10, Charlson score: OR 0.90 (0.61-1.34), p = 0.60, ASA classes 3-4: OR 3.45 (0.66-17.95), p = 0.14. ***Full model: age: HR 1.08 (0.96-1.22), p = 0.21, Charlson score: HR 1.07 (0.96-1.27), p = 0.41, ASA classes 3-4: HR 1.10 (0.58-2.09), p = 0.77