Table 1 Cohort characteristics stratified by perioperative treatment
Variable | No treatment | MMC | CSBI | p-value |
|---|---|---|---|---|
Total no. of patients | 89 | 71 | 45 | – |
Age, mean (SD) | 73.2 (11.2) | 68.2 (12.3) | 75.3 (8.9) | < 0.002+ |
Gender, n (%) | 0.54 | |||
Male | 75 (84.3) | 55 (77.5) | 37 (83.2) | |
Female | 14 (15.7) | 16 (22.5) | 8 (17.8) | |
Grade, n (%) | 0.9 | |||
High | 45 (50.6) | 34 (47.9) | 21 (46.7) | |
Low | 44 (49.4) | 37 (52.1) | 24 (53.3) | |
Stage, n (%) | 0.03* | |||
Ta without CIS | 55 (61.8) | 41 (57.8) | 30 (66.7) | |
Ta with CIS | 3 (3.4) | 4 (5.6) | 5 (11.1) | |
T1 without CIS | 13 (14.6) | 18 (25.4) | 5 (11.1) | |
T1 with CIS | 4 (4.5) | 6 (8.5) | 3 (6.7) | |
CIS only | 14 (15.7) | 2 (2.8) | 2 (4.4) | |
Tumor size, n (%) | 0.12* | |||
< 0.5 cm | 11 (12.36) | 3 (4.2) | 6 (13.3) | |
0.5–2.0 cm | 33 (37.1) | 41 (57.8) | 16 (35.6) | |
2.0–5.0 cm | 22 (24.7) | 13 (18.3) | 10 (22.2) | |
> 5.0 cm | 23 (25.8) | 14 (19.7) | 13 (28.9) | |
Multiple tumors, n (%) | 47 (52.8) | 36 (50.7) | 22 (48.9) | 0.91 |
Recurrent disease, n (%) | 40 (45.0) | 23 (32.4) | 12 (26.7) | 0.08 |
AUA Risk Stratification | 0.72 | |||
Low risk | 10 (11.2) | 6 (8.5) | 7 (15.6) | |
Intermediate risk | 34 (38.2) | 31 (43.7) | 15 (33.3) | |
High risk | 45 (50.6) | 34 (47.9) | 23 (51.1) | |
Restaging resection, n (%) | 8 (9.0) | 18 (25.4) | 10 (22.2) | 0.02 |
Adjuvant therapy, n (%) | 35 (39.3) | 35 (49.3) | 16 (35.6) | 0.28 |
Follow-up in months, median [IQR] | 14 [6–28] | 23 [11–32] | 13 [9–19] | < 0.01§ |