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Table 2 Cohort characteristics stratified by Recurrence or Progression

From: Continuous saline bladder irrigation for two hours following transurethral resection of bladder tumors in patients with non-muscle invasive bladder cancer does not prevent recurrence or progression compared with intravesical Mitomycin-C

Variable

Recurrence or Progression

No Recurrence or Progression

p-value

Total no. of patients

90

115

Age, mean (SD)

73.6 (10.8)

70.6 (11.8)

0.07+

Gender, n (%)

  

0.81

 Male

74 (82.2)

93 (80.9)

 

 Female

16 (17.8)

22 (19.1)

Grade, n (%)

  

0.38

 High

47 (52.2)

53 (46.1)

 

 Low

43 (47.8)

62 (53.9)

Stage, n (%)

  

0.09*

 Ta without CIS

55 (61.1)

71 (61.7)

 

 Ta with CIS

3 (3.3)

9 (7.8)

 T1 without CIS

14 (15.6)

22 (19.1)

 T1 with CIS

5 (5.6)

8 (7.0)

 CIS

13 (14.4)

5 (4.4)

Tumor size, n (%)

  

0.09

  < 0.5 cm

14 (15.6)

6 (5.2)

 

 0.5–2.0 cm

37 (41.1)

53 (46.1)

 2.0–5.0 cm

17 (18.9)

28 (24.4)

  > 5.0 cm

22 (24.4)

28 (24.3)

Multiplicity of tumor, n (%)

56 (62.2)

49 (42.6)

< 0.01

Recurrent disease, n (%)

42 (46.7)

33 (28.7)

< 0.01

AUA Risk Stratification

  

0.07

 Low risk

9 (10.0)

14 (12.2)

 

 Intermediate risk

28 (31.1)

52 (45.2)

 High risk

53 (58.9)

49 (42.6)

Restaging resection, n (%)

12 (13.3)

24 (20.9)

0.16

Adjuvant therapy, n (%)

32 (35.6)

54 (47.0)

0.10

Perioperative treatment, n (%)

  

0.004

 None

47 (52.2)

42 (36.5)

 

 MMC

20 (22.2)

51 (44.4)

 CSBI

23 (25.6)

22 (19.1)

  1. MMC Mitomycin-C, CSBI continuous saline bladder irrigation, SD standard deviation, CIS carcinoma in situ. +One-way ANOVA. *Fisher’s exact test