Continuous saline bladder irrigation for two hours following transurethral resection of bladder tumors in patients with non-muscle invasive bladder cancer does not prevent recurrence or progression compared with intravesical Mitomycin-C

Table 3 Cox multivariable model for Recurrence or Progression

Variable	Hazard Ratio	95% Confidence Interval	p-value
Age (per year of age)	1.00	0.98–1.02	0.92
AUA Risk Stratification
Low Risk	Reference	Reference
Intermediate Risk	0.84	0.39–1.80	0.66
High Risk	2.77	1.28–6.01	0.01
Adjuvant therapy
No	Reference	Reference
Yes	0.35	0.20–0.59	< 0.001
Perioperative treatment
No perioperative treatment	Reference	Reference
MMC	0.43	0.25–0.75	0.003
CSBI	0.96	0.58–1.60	0.89

LG low grade, HG high grade, CIS carcinoma in situ, MMC Mitomycin-C, CSBI continuous saline bladder irrigation

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