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Fig. 5 | BMC Urology

Fig. 5

From: Epidermal growth factor expression as a predictor of chemotherapeutic resistance in muscle-invasive bladder cancer

Fig. 5

Gene silencing of EGFR enhances drug sensitivity to cisplatin treatment. (a and b, TCCSUP; c and d; T24) Transiently transfected TCCSUP (a) or T24 (c) cells with siRNA of EGFR were treated with cisplatin (0, 1, 5 and 10 μM). Cisplatin was added together with siNRA for 48 h and then re-treated with cisplatin. Cell viability was measured by MTS assay after 2 days. Overexpression of siEGFR, but not a control siRNA, in TCCSUP (c) or T24 (d) cells reduced cell proliferation (Student’s t-test, *p < 0.05)

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BMC Urology

ISSN: 1471-2490

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