Table 1 Summary of published sunitinib withdrawal phenomenon cases
Ref, year | Age/sex | Location | Dose and length of sunitinib treatment | Reason for discontinuing sunitinib treatment | Interval between spontaneous regression and sunitinib |
|---|---|---|---|---|---|
Rothermundt, 2009 [17] | 63/F | bilateral adrenal glands, lung and bone | sunitinib 50 mg 4 weeks on and 2 weeks off, 10 months | disease progression | 1 month |
Yanagihara, 2011 [18] | 61/F | bone and liver | sunitinib 50 mg per day, 11 days | thrombocytopenia and digestive symptoms | 18 months |
Teo, 2013 [6] | 65/M | lung | 50 mg/d, 4 weeks on and 2 weeks off for 6 months and 37.5 mg per day for 9 months | disease progression | No mention |