Ameliorative effects of rutin against cisplatin-induced reproductive toxicity in male rats

BMC Urology

Table 3 Morphometrical evaluation of testicular tissue in different treatment

Groups (n = 4)	Interstitial space (μm)	Tunica albugenia height (μm)	Seminiferous tubule diameter (μm)	Seminiferous tubule epithelial height (μm)	Tubular lumen (μm)
Control	2.41 ± 0.05	30.55 ± 0.37	248.39 ± 3.04	98.50 ± 0.92	22.03 ± 0.38
Cisplatin	11.86 ± 0.11^a***	15.96 ± 0.53^a***	215.03 ± 2.72^a***	50.59 ± 0.61^a***	51.42 ± 1.4^a***
Cisplatin + Rutin	5.75 ± 0.14^b*	22 ± 0.53	238.56 ± 3.97^b**	67.52 ± 0.62^ab***	25.69 ± 1.65^b**
Rutin	4.28 ± 0.09	28.49 ± 0.42	240 ± 2.93	76.6 ± 0.7^a**	29.6 ± 0.91

Values are expressed as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, ^a = Value vs control,^b = Value vs cisplatin

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