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Table 3 Per patient cost of prostate cancer in France, Germany, United Kingdom and Canada

From: Literature review of the burden of prostate cancer in Germany, France, the United Kingdom and Canada

Study (year)

Description of cost

Cost year

Currency

Mean cost

France

 Fourcade et al. (2010) [17]

Total direct cost of treatment in 12 months after diagnosis, excluding follow up and adverse event costs, for all diagnosed patients

2006

EUR

5851

 Molinier et al. (2011) [44]

Mean total cost (all prostate cancer)

2008

EUR

12,731

Mean total cost localized

2008

EUR

12,259

Mean total cost regional

2008

EUR

16,608

Mean total cost metastatic

2008

EUR

9994

Germany

 Fourcade et al. (2010) [17]

Total direct cost of treatment in 12 months after diagnosis, excluding follow up and AE costs, for all diagnosed patients

2006

EUR

3698

UK

 Hall et al. (2015) [45]

Cumulative hospital-based costs of care over 15 months following initial diagnosis in patients treated with curative intent

2011/12

GBP

3722 (95% CI, 3263–4208)

 Fourcade et al. (2010) [17]

Total direct cost of treatment in 12 months after diagnosis, excluding follow up and AE costs, for all diagnosed patients

2006

EUR

3682

 Marti et al. (2016) [46]

Total societal (and component costs) in prostate cancer survivors treated with curative intent over 12–15 months post-diagnosis period

   

Total societal cost (per month)

2012

GBP

117.9 (95% CI: 68.9–167.0)

NHS costs (per month)

2012

GBP

92.1 (49.3–134.9)

Patient OOP costs (per month)

2012

GBP

7.2 (2.3–12.0)

Informal care costs (per month)

2012

GBP

16.4 (−5.5–38.3)

Canada

 De Oliveira et al. (2013) [47]

Total healthcare costs in 12 months after diagnosis in patients aged ≥45 years

2009a

CAD

15,170

 Krahn et al. (2010) [48]

Direct medical costs for men diagnosed 1995–2002 according to phase

2004

CAD

 

Phase Ib (costs incurred in 6 months prior to prostate cancer diagnosis)

2004

CAD

1904

Phase IIb (costs incurred in first 12 months after prostate cancer diagnosis)

2004

CAD

12,005

Phase IIIb (“continued care” phase, costs per 100 days)

2004

CAD

1495

Phase IVb (pre-terminal care in 18 to 6 months before death)

2004

CAD

20,543

Phase Vb (terminal care, 6 months before death)

2004

CAD

28,834

 De Oliveira et al. (2014) [49]

Patient time costs per year (all)

2006

CAD

838 (442–1233)

Out of pocket costs per year (all)

2006

CAD

200 (109–290)

 Krahn et al. (2014) [50]

Early health states: non-treated, non-metastatica

2008

CAD

3440

Early health states: radiation therapya

2008

CAD

2160

Early health states: radical prostatectomya

2008

CAD

4676

Early health states: hormone therapya

2008

CAD

3357

Middle health states: post-radiation therapya

2008

CAD

1556

Middle health states: post-radical prostatectomya

2008

CAD

732

Middle health states: recurrence/progressiona

2008

CAD

1919

Late health states: hormone therapy refractorya

2008

CAD

4503

Late health states: metastatica

2008

CAD

4062

Late health states: metastatic refractorya

2008

CAD

6398

Late health states: finala

2008

CAD

13,739

 Sanyal et al. (2016) [51]

Total overall cost (overall cohort) at:

   

5 years

2014

CAD

18,503 (17,851–19,185)

10 years

2014

CAD

28,032 (26,129–29,973)

15 years

2014

CAD

39,143 (36,606–41,821)

 Dragomir et al. (2014) [52]

Active surveillance; cost first 5 years

2012

CAD

6200 (6083 to 6317)

Immediate treatment; cost first 5 years

2012

CAD

13,735 (13,615 to 13,855)

  1. aCost per 100 days