Impact of bilateral biopsy-detected prostate cancer on an active surveillance population

BMC Urology

Table 2 Regression analysis of clinical and pathologic features predicting active surveillance failure

Variables	Univariable COX regression			Multivariable COX regression
Variables	HR	95% CI	p-Value	HR	95% CI	p-Value
Bilateral tumor on Bx	4.09	2.22–7.53	< 0.0001*	3.8	2.05–7.06	< 0.0001*
MCI	1.01	0.98–1.05	0.418
PSA	1.02	0.90–1.16	0.747
PSA density	1.32	0.88–1.98	0.186	1.34	0.85–2.11	0.21
BMI	1	0.94–1.07	0.995
Prostate Volume	0.99	0.97–1.00	0.131
Previous (−) Biopsy	0.91	0.48–1.75	0.78

Prostate Specific Antigen (PSA), Body Max Index (BMI), Maximal Percentage of the most involved core (MCI), Prostate Biopsy (Bx)

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