Variable | univariable cox regression analysis | multivariable cox regression analysis | ||||
---|---|---|---|---|---|---|
Hazard Ratio | 95% CI | p | Hazard Ratio | 95% CI | p | |
Age (continuous) | 1.034 | 1.003–1.067 | 0.034 | 1.027 | 0.994–1.061 | 0.108 |
Preoperative stage | 0.113 | 0.927 | ||||
Ta and Tis and T1 | – | referent | – | – | Referent | – |
T2 | 1.317 | 0.552–3.141 | 0.535 | 0.814 | 0.281–2.359 | 0.705 |
T3 | 2.496 | 1.064–5.851 | 0.035 | 1.050 | 0.355–3.100 | 0.930 |
T4 | 2.608 | 0.683–9.951 | 0.161 | 0.862 | 0.174–4.264 | 0.856 |
Pathologic stage | 0.005 | 0.129 | ||||
Ta and Tis and T1 | – | referent | – | – | referent | – |
T2 | 1.375 | 0.530–3.568 | 0.513 | 1.315 | 0.456–3.792 | 0.613 |
T3 and T4 | 3.341 | 1.427–7.822 | 0.005 | 2.508 | 0.876–7.174 | 0.087 |
Pathologic nodal stage | ||||||
N0 | – | referent | – | – | Referent | – |
N+ | 2.725 | 1.285–5.778 | 0.009 | 1.896 | 0.791–4.544 | 0.152 |
No chemotherapy | – | referent | – | – | Referent | – |
Chemotherapy | 2.979 | 1.486–5.973 | 0.002 | 1.860 | 0.848–4.081 | 0.121 |
Location of the tumor | ||||||
other location | – | referent | – | – | Referent | – |
posterior wall/trigone | 2.028 | 0.934–4.402 | 0.074 | 1.902 | 0.834–4.339 | 0.126 |
Negative margin | – | referent | – | – | Referent | – |
Positive margin | 3.938 | 1.177–13.172 | 0.026 | 1.463 | 0.381–5.628 | 0.580 |
No hysterectomy | – | referent | – | – | Referent | – |
Hysterectomy | 0.976 | 0.520–1.832 | 0.976 | 0.908 | 0.428–1.924 | 0.801 |