Table 4 Hazard ratios of biochemical recurrence (BR) in multivariate model and BR-free survival following radical prostatectomy in men with fPSM or ePSM
Study | Year | n | fPSM no. (%) | ePSM no. (%) | Median follow-up, yr. | HR for BR (95% CI) ePSM vs fPSM p value | BR-free survival at 5 years for fPSM (%) | BR-free survival at 5 years for ePSM (%) | Including ≥pT3b, N+, neo or adjuvant treatment |
|---|---|---|---|---|---|---|---|---|---|
Lake et al. [14] | 2010 | 2022 | 344 (17.0) | 99 (4.9) | 4.1 | NR | 72 | 62 | Yes |
Lee e al [15] | 2015 | 1733 | 114 (6.6) | 359 (20.7) | 4 | NR | 83 | 54 | Yes |
Sooriakumaran et al. [25] | 2013 | 893 | 100 (11.2) | 81 (9.1) | 5 | 2.43 (1.14–5.18) < 0.05 | 81 | 65 | Yes |
Stenphenson et al. [27] | 2009 | 1501 | 983 (65.5) | 518 (34.5) | 7 | 1.3 (1.1–1.6) 0.004 | 63 | 43 | No |
May et al. [28] | 2011 | 1036 | 122 (11.8) | 145 (14.0) | 4.3 | 1.0 (0.66–1.55) 0.96 | 49 | 51 | No |
Porpiglia et al. [29] a | 2012 | 300 | 48 (16.0) | 20 (6.7) | 5.1 | 5.7 (1.5–2.17) 0.01 | 77 | 55 | Yes |
Ochiai et al. [30] | 2007 | 117 | 81 (69.2) | 32 (27.4) | 3.6 | NR | 84 | 52 | Yes |
Van Oort et al. [31] | 2010 | 174 | NR | NR | 3.6 | 2.15 (1.12–4.2) 0.02 | NR | NR | Yes |