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Table 2 Crude and adjusted odds ratios (OR) with 95% confidence interval (95%CI), for associations between distress and PSA, sociodemographic factors, hormonal therapy (surgical or medical) and overall QoL (n = 3165)

From: Prostate-specific antigen (PSA) and distress: - a cross-sectional nationwide survey in men with prostate cancer in Sweden

Variable

Model 1a

Model 2b

Model 3c

OR

(95% CI)

p

OR

(95% CI)

p

OR

(95% CI)

p

Age n = 3141

 41–73

1

  

-

  

-

  

 74–95

0.90

(0.78–1.04)

0.14

      

Years since diagnosis n = 3051

 0–6

1

  

-

  

-

  

 7–43

1.10

(0.96–1.27)

0.18

      

Quality of life n = 3118

 7–10

1

  

-

  

1

  

 0–6

4.49

(3.81–5.29)

0.00

   

4.33

(3.62–5.17)

0.00

Marital status n = 2970

 Married/cohabiting/in a relationship

1

  

1

  

1

  

 Single/widowed/divorced

1.50

(1.19–1.88)

0.00

1.40

(1.10–1.77)

0.01

1.16

(0.90–1.49)

0.25

Education n = 3036

 Elementary school

1

  

1

  

1

  

 High school

1.04

(0.87–1.24)

0.83

1.06

(0.89–1.28)

0.50

1.21

(1.00–1.47)

0.05

 University

0.83

(0.70–0.99)

0.02

0.85

(0.71–1.01)

0.07

1.00

(0.83–1.21)

0.98

PSA (ng/ml) n = 3165

 0–19

1

  

1

  

1

  

 20–99

1.36

(1.11–1.66)

0.00

1.25

(1.01–1.55)

0.04

1.21

(0.96–1.51)

0.10

 100–999

1.54

(1.19–2.01)

0.00

1.47

(1.12–1.94)

0.01

1.25

(0.93–1.68)

0.14

 1000–

2.19

(1.38–3.47)

0.00

1.77

(1.11–2.85)

0.02

1.17

(0.70–1.94)

0.55

Hormonal therapy n = 3165

 No

1

  

1

  

1

  

 Yes

1.42

(1.18–1.71)

0.00

1.35

(1.11–1.65)

0.00

1.12

(0.91–1.39)

0.28

  1. p ≤ 0.05, significant values in bold
  2. aModel 1: Bivariate association between all variables and distress
  3. bModel 2: Association between PSA-value and distress adjusted for all significant independent variables in Model 1 excluding QoL
  4. cModel 3: Association between PSA-values and distress adjusted for all significant independent variables in Model 1 also including QoL