Table 1 Cohort characteristics
Characteristics N = 4336 | Active surveillance | p-value | |
|---|---|---|---|
no | yes | ||
Total - n (%) | 2298 (53) | 2038 (47) | |
Age - mean (SD) | 62.2 (6.6) | 63.9 (5.7) | < 0.001 |
Cancer characteristics- median (IQR) | |||
PSA at diagnosis | 5 (3.8–6.6) | 4.6 (3.4–6.1) | < 0.001 |
Max cancer length | 5 (2–11) | 2 (1–4) | < 0.001 |
Positive cores | 2 (1–4) | 1 (1–2) | < 0.001 |
Prostate volume | 35 (26–46) | 40 (30–51) | < 0.001 |
Stage: | |||
T1c - n (%) | 1800 (78) | 1827 (90) | < 0.001 |
T2 - n (%) | 498 (22) | 211 (10) | |
Risk Category (Swedish guidelines) - n (%): | |||
Very low risk | 552 (24) | 1114 (55) | < 0.001 |
Low risk | 1746 (76) | 924 (45) | |
Reason for presentation - n (%) | |||
Health check | 1412 (61) | 1542 (76) | < 0.001 |
LUTS | 397 (17) | 297 (15) | |
Other symptoms | 257 (11) | 153 (8) | |
Unknown | 218 (10) | 41 (2) | |
Comorbidity (CCI at diagnosis) | |||
0 | 2012 (88) | 1764 (86) | 0.531 |
1 | 179 (8) | 178 (9) | |
2 | 75 (3) | 72 (4) | |
3+ | 30 (1) | 32 (2) | |
Year of diagnosis - n (%) | |||
2008 | 337 (15) | 127 (6) | < 0.001 |
2009 | 413 (18) | 160 (8) | |
2010 | 323 (14) | 154 (8) | |
2011 | 242 (11) | 178 (9) | |
2012 | 247 (11) | 209 (10) | |
2013 | 313 (14) | 415 (20) | |
2014 | 423 (18) | 795 (39) | |
Education level - n (%) | |||
< High school | 323 (14) | 320 (16) | 0.073 |
High school | 940 (41) | 867 (43) | |
Post high school< 3 yrs | 330 (14) | 296 (15) | |
University | 687 (30) | 541 (27) | |
missing | 18 (1) | 14 (1) | |
Civil Status | |||
Not married/widowed | 749 (33) | 719 (35) | 0.063 |
Married/partner | 1549 (67) | 1319 (65) | |
History of PCa in family - n (%) | |||
No | 1713 (75) | 1621 (80) | < 0.001 |
Yes | 583 (25) | 415 (20) | |
TREATMENTS - n (%) | |||
Active surveillance | 0 (0) | 2038 (100) | |
Curative | 1604 (69) | 0 (0) | |
Watchful waiting | 209 (9) | 0 (0) | |
Treatment unknown | 485 (21) | 0 (0) | |