Is there any association between prostate-specific antigen screening frequency and uptake of active surveillance in men with low or very low risk prostate cancer?

Table 2 PSA testing and prostate biopsy history in the 5 years prior to diagnosis of prostate cancer

Measures	Active surveillance		p-value
Measures	no	yes	p-value
Prior PSA tests - Mean (sd)
Total no. PSA tests	4.0 (2.6)	3.9 (2.7)	0.322
No. PSA tests excluding confirmatory tests	3.3 (2.3)	3.2 (2.2)	0.597
Screening interval (days)^a	304 (281)	333 (313)	0.003
Mean pre-diagnostic total PSA level	4.6 (1.9)	4.3 (2.1)	0.001
Highest pre-diagnostic total PSA level	5.8 (3.1)	5.4 (3.6)	0.001
PSA velocity (ng/mL/year)^a	0.46 (1.6)	0.42 (1.7)	0.001
No. biopsies prior to diagnosis No. (%)
None	2001 (87)	1771 (87)	0.934
1	235 (10)	211 (10)
2	48 (2)	46 (2)
3+	14 (1)	10 (0.5)

ISSN: 1471-2490