Table 1 Study design characteristics of included studies in meta-analysis
Study | Year | Region/Country | Study period | Study design | Database | No. of patients | Intervention | Control | Inclusion criteria | Exclusion criteria | Outcome | Quality score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alam R et al [14] | 2018 | USA | 2009-NA | Prospective cohort | Delayed Intervention and Surveillance for Small Renal Masses Registry | 597 | PN, TA (CA, RFA) | AS | Age > 18, cT1a renal mass | History of RCC, familial RCC syndrome, or suspicion of a second malignancy metastasis | CSS, OS | 9 |
Miller BL et al [15] | 2018 | USA | 2003–2016 | Retrospective | Single center data | 135 | PN, TA | AS | Histological diagnosis of oncocytoma or chRCC (cT1–2) | NA | CSS, OS | 7 |
Tang DH et al [16] | 2017 | USA | 2000–2013 | Retrospective | Single center data | 62 | PN | AS | Age 80–89, cT1–2 renal mass | NA | CSS, OS | 7 |
Larcher A et al [17] | 2015 | USA | 2000–2009 | Retrospective | SEER-Medicare-linked database | 1860 | TA | AS | T1aN0M0, unilateral RCC | RCC diagnosed only on death | CSS | 9 |
Patel HD et al [18] | 2015 | USA | 1995–2007 | Retrospective | SEER-Medicare-linked database | 2603 | PN | AS | cT1aN0M0 renal cortical tumor | cT3–4, N1–2, M1, unknown classification, urothelial carcinoma, noncortical renal tumors, multiple procedures, bilateral tumors, previous diagnosis of another cancer, undergone TA | CSS, OS, CVSS | 8 |
Patel N et al [19] | 2012 | UK | 2005–2010 | Retrospective | Cancer Research Uro-Oncology Database | 161 | PN | AS | cT1aN0M0 renal mass | NA | CSS, OS | 7 |
Lane BR et al [20] | 2010 | USA | 2000–2006 | Retrospective | Single center data | 391 | open/laparoscopic PN, TA (CA, RFA) | AS | Age > 75, cT1 renal tumor | Not suspicious renal tumor, PN for other reason | CSS, OS, CVSS | 8 |