Table 1 Clinicopathological features of patients undergoing radical cystectomy and pelvic lymphadenectomy
Group 1 | Group 2 | Group 3 | Group 4 | P value | |
|---|---|---|---|---|---|
PVLN(−)/non-PVLN(−) | PVLN(+)/non-PVLN(−) | PVLN(−)/non-PVLN(+) | PVLN(+)/non-PVLN(+) | ||
No. of patients | 76 | 5 | 17 | 17 | |
Age (mean ± SD, years) | 67.6 ± 12.5 | 73.8 ± 11.0 | 70.8 ± 8.9 | 68.9 ± 9.7 | > 0.1a |
Sex | > 0.1a | ||||
Male | 60 (79%) | 4 (80%) | 13 (76%) | 16 (94%) | |
Female | 16 (21%) | 1 (20%) | 4 (24%) | 1 (6%) | |
Clinical stage (prior to cystectomy) | 0.021b (G1 vs G4); 0.039b (G1 vs G2&G4); 0.034b (G1 vs G2-G4) | ||||
≤ II | 61 (80%) | 4 (80%) | 13 (76%) | 10 (59%) | |
≥ III | 8 (11%) | 1 (20%) | 4 (24%) | 6 (35%) | |
Unknown | 7 (9%) | 0 (0%) | 0 (0%) | 1 (6%) | |
Neoadjuvant chemotherapy | > 0.1a | ||||
No | 65 (86%) | 4 (80%) | 12 (71%) | 13 (76%) | |
Yes | 11 (14%) | 1 (20%) | 5 (29%) | 4 (24%) | |
Histology | > 0.1a | ||||
Conventional | 56 (74%) | 5 (100%) | 14 (82%) | 10 (59%) | |
Variants | 20 (26%) | 0 (0%) | 3 (18%) | 7 (41%) | |
pT stage | 0.013 (G1 vs G3); < 0.001 (G1 vs G4); < 0.001 (G1 vs G2&G4); < 0.001 (G1 vs G2-G4) | ||||
≤ 2 | 49 (64%) | 2 (40%) | 5 (29%) | 1 (6%) | |
≥ 3 | 27 (36%) | 3 (60%) | 12 (71%) | 16 (94%) | |
Surgical margin | > 0.1a | ||||
No | 71 (93%) | 4 (80%) | 17 (100%) | 14 (82%) | |
Yes | 5 (7%) | 1 (20%) | 0 (0%) | 3 (18%) | |
Adjuvant therapy | 0.006 (G1 vs G4); 0.010 (G1 vs G2&G4); 0.010 (G1 vs G2-G4) | ||||
No | 65 (86%) | 4 (80%) | 12 (71%) | 9 (53%) | |
Yes | 11 (14%) | 1 (20%) | 5 (29%) | 8 (47%) |