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Fig. 3 | BMC Urology

Fig. 3

From: Limited utility of qPCR-based detection of tumor-specific circulating mRNAs in whole blood from clear cell renal cell carcinoma patients

Fig. 3

Blood relative mRNA expression of CDK18, CCND1, and LOX based on the qBase exported relative quantity (RQ) values, calculated from Cq values, according to the formula: RQ = 2 (meanCq-Cq); results from qBase (RQ values) were processed in GraphPad Prism in order to generate graphs using the Mann-Whitney U-test. N- normal patient samples; T- tumor patient samples; mT- metastatic. a CDK18 was underexpressed in PAX blood tumor samples compared to normal PAX blood. b There is no significant difference in expression of CDK18 between tumor and metastatic tumor PAX blood samples. c CCND1 was underexpressed in PAX blood tumor samples compared to normal PAX blood. d There is no significant difference in expression of CCND1 between tumor and metastatic tumor PAX blood samples. e There is no significant difference in expression of LOX in PAX blood tumor samples compared to normal PAX blood. f Lox shows a tendency towards upregulation in metastatic compared to non-metastatic tumor PAX blood samples

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BMC Urology

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