From: Differential expression of histamine receptors in the bladder wall tissues of patients with bladder pain syndrome/interstitial cystitis – significance in the responsiveness to antihistamine treatment and disease symptoms
Groups
Number of cases
H1R
H2R
H3R
H4R
IC patients
69
0.1389 ± 0.05115
0.0861 ± 0.01646
0.1124 ± 0.04665
0.1007 ± 0.02212
Control Subjects
10
0.0395 ± 0.00361
0.0633 ± 0.00809
0.0842 ± 0.01632
0.0576 ± 0.00982
P- value
0.000
0.031
0.008
0.048