The association of pathogenic factors of metabolic syndrome on serum prostate-specific antigen levels: a pilot study

Table 3 Analysis of MetS-related affect PSA

Characteristics	B	95% CI	†P-value	B	95% CI	‡P-value
Insulin	−0.241	− 0.492, 0.009	0.049	− 0.172	−0.272, -0.073	<0.001
HOMA index	0.076	−0.169, 0.321	0.542
DHT	−0.089	−0.184, 0.006	0.068
SHBG	−0.182	−0.305, -0.058	0.004	−0.163	− 0.284, -0.042	<0.001
Estradiol	0.062	−0.028, 0.153	0.177
Testosterone	0.128	0.006, 0.251	0.039	0.083	−0.032, 0.198	0.158
Leptin	−0.033	0.159, 0.093	0.607
Resistin	0.061	−0.030, 0.153	0.186
Adiponectin	0.041	−0.058, 0.140	0.412
CRP	0.032	−0.064, 0.129	0.510
IL-6	−0.072	−0.175, 0.031	0.169
TNF-α	−0.025	−0.122, 0.072	0.617

Abbreviations as in Table 1 and Table 2
†P-values were separately calculated three different statistics model according to multivariate linear regression analyses after adjustment of age, BMI, prostate volume and HDL-C;The model 1 include Insulin and HOMA index;The model 2 include DHT, SHBG, Estradiol, Testosterone; The model 3 include Leptin, Resistin, Adiponectin, CRP, IL-6, TNF-α;
‡P-value were calculated statistics model include Insulin, SHBG, Testosterone according to multivariate linear regression analyses after adjustment of age, BMI, prostate volume and HDL-C;
Bold indicates statistically significant

ISSN: 1471-2490