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Table 1 Baseline characteristics of the patients in the IAC and NIAC before and after matched groups (1:3)

From: The long-term efficacy of one-shot neoadjuvant intra-arterial chemotherapy combined with radical cystectomy versus radical cystectomy alone for bladder cancer: a propensity-score matching study

 

Intra-arterial

Before matched groups

After matched groups (1:3)

No intra-arterial

p value

No intra-arterial

p value

Patients (n)

26

123

 

78

 

Gender

1.000

1.000

Female, n (%)

4(15.4%)

19(15.4%)

10(12.8%)

Male, n (%)

22(84.6%)

104(84.6%)

68(87.2%)

Age, yr, median (IQR)

60.0(55.0–71.0)

63.0(56.0–72.0)

0.328

62.5(56.0–69.3)

0.799

Body mass index (kg/m2)

25.2 ± 3.12

24.1 ± 3.8

0.184

24.3 ± 3.1

0.202

Hypertension, n (%)

12(46.2%)

38(30.9%)

0.134

27(34.6%)

0.293

Diabetes, n (%)

4(15.4%)

16(13.0%)

0.995

8(10.3%)

0.723

Age-adjusted CCI

4.0(3.0–7.0)

4.0(3.0–5.0)

0.625

4.0(3.0–6.0)

0.909

ASA score

2.0(1.8–2.0)

2.0(2.0–2.0)

0.221

2.0(2.0–2.0)

0.188

ECOG PS

1.0(0.0–1.0)

1.0(0.0–1.0)

0.490

1.0(1.0–1.0)

0.394

Smoking history, n (%)

15(57.7%)

58(47.2%)

0.329

40(51.3%)

0.571

Time between confirmed tumor and RC, mo, median (IQR)

3.0(1.0–6.8)

5.0(1.0–18.0)

0.133

5.0(1.0–18.0)

0.173

TURBT before RC

7(25.9%)

57(46.3%)

0.048

32(41.0%)

0.100

Preoperative irradiation, n (%)

0(0.0%)

5(4.1%)

0.587

3(3.8%)

0.571

Follow-up length, mo, median (IQR)

88.0(37.0–109.0)

26.0(14.0–65.0)

0.002

56.0(30.8–91.3)

0.161

  1. IAC, intra-arterial chemotherapy; NIAC, no-intra-arterial chemotherapy; IQR = interquartile range; RC = radical cystectomy; ASA = American Society of Anesthesiologists; CCI = Charlson comorbidity index; ECOG PS = Eastern Cooperative Oncology Group performance status