Skip to main content

Table 1 Patient sociodemographic characteristics and clinical risk factors by race

From: A comparative effectiveness analysis of the PBCG vs. PCPT risks calculators in a multi-ethnic cohort

Continuous Variables

Black (n = 463)

White (n = 355)

Other (n = 136)

p Value 1

Median [IQR]

Median [IQR]

Median [IQR]

Age, years

61.0 [57.0, 67.0]

62.0 [58.0, 67.0]

62.0 [57.0, 67.0]

0.47

BMI, kg/m 2

27.8 [24.5, 31.8]

27.5 [25.0, 30.6]

27.4 [24.2, 30.3]

0.56

PSA, ng/ml

7.8 [5.3, 15.5]

4.8 [3.6, 7.3]

7.2 [5.1, 12.4]

< 0.001

Prostate Volume, cm 3

39.5 [28.8, 55.4]

39.5 [29.7, 51.0]

48.7 [30.0, 69.4]

< 0.001

PSA density, ng/cm3

0.23 [0.12,0.43]

0.13 [0.09, 0.20]

0.18 [0.11, 0.32]

< 0.001

PCPT csPCa Risk, %

25.0 [17.0, 40.0]

7.0 [5.0, 12.0]

11.5 [7.0, 18.0]

< 0.001

PBCG csPCa Risk, %

45.0 [31.0, 65.0]

26.0 [18.0, 41.0]

37.5 [22.0, 54.2]

< 0.001

Categorical Variables

Black n (%)

White n (%)

Other n (%)

p Value2

Clinical Risk Factors

 Family History of PCa

93 (20.1)

88 (24.8)

21 (15.4)

0.055

 Abnormal DRE

140 (30.3)

112 (31.5)

43 (31.3)

0.92

 BPH/LUTS

151 (32.6)

135 (38.0)

66 (48.5)

0.003

 5-ARI Use (current)

43 (9.3)

19 (5.4)

26 (19.1)

< 0.001

Substance Use History

 Heavy Smoking (>1ppd)

29 (6.4)

19 (5.4)

1 (0.7)

0.034

 Heavy Alcohol Use (> 10 drinks/week)

30 (6.6)

46 (13.0)

5 (3.7)

< 0.001

Demographic Factors

 Married

192 (42.1)

269 (76.2)

105 (77.2)

< 0.001

 College Completion

165 (36.2)

248 (70.3)

46 (33.8)

< 0.001

 Income < $30,000

161 (43.9)

39 (12.0)

42 (55.2)

< 0.001

Biopsy Outcomes

   

< 0.0013

 Indolent Cancer

167 (36.1)

118 (33.2)

38 (27.9)

0.20

 Clinically Significant Cancer

175 (37.8)

120 (33.8)

26 (19.1)

< 0.001

 No Cancer

121 (26.1)

117 (33.0)

72 (52.9)

< 0.001

  1. 1Using Kruskal-Wallis tests; 2Using Pearson-χ2 tests; 3χ2 trend test. Bold type indicates p values < 0.05. Abbreviations: BMI body mass Index, PSA prostate specific antigen, BPH/LUTS clinical diagnosis of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms, DRE digital rectal examination, csPCa clinically significant prostate cancer, PBCG Prostate Biopsy Collaborative Group, PCPT Prostate Cancer Prevention Trial, ppd pack per day