From: A comparative effectiveness analysis of the PBCG vs. PCPT risks calculators in a multi-ethnic cohort
Continuous Variables | Black (n = 463) | White (n = 355) | Other (n = 136) | p Value 1 |
---|---|---|---|---|
Median [IQR] | Median [IQR] | Median [IQR] | ||
Age, years | 61.0 [57.0, 67.0] | 62.0 [58.0, 67.0] | 62.0 [57.0, 67.0] | 0.47 |
BMI, kg/m 2 | 27.8 [24.5, 31.8] | 27.5 [25.0, 30.6] | 27.4 [24.2, 30.3] | 0.56 |
PSA, ng/ml | 7.8 [5.3, 15.5] | 4.8 [3.6, 7.3] | 7.2 [5.1, 12.4] | < 0.001 |
Prostate Volume, cm 3 | 39.5 [28.8, 55.4] | 39.5 [29.7, 51.0] | 48.7 [30.0, 69.4] | < 0.001 |
PSA density, ng/cm3 | 0.23 [0.12,0.43] | 0.13 [0.09, 0.20] | 0.18 [0.11, 0.32] | < 0.001 |
PCPT csPCa Risk, % | 25.0 [17.0, 40.0] | 7.0 [5.0, 12.0] | 11.5 [7.0, 18.0] | < 0.001 |
PBCG csPCa Risk, % | 45.0 [31.0, 65.0] | 26.0 [18.0, 41.0] | 37.5 [22.0, 54.2] | < 0.001 |
Categorical Variables | Black n (%) | White n (%) | Other n (%) | p Value2 |
Clinical Risk Factors | ||||
Family History of PCa | 93 (20.1) | 88 (24.8) | 21 (15.4) | 0.055 |
Abnormal DRE | 140 (30.3) | 112 (31.5) | 43 (31.3) | 0.92 |
BPH/LUTS | 151 (32.6) | 135 (38.0) | 66 (48.5) | 0.003 |
5-ARI Use (current) | 43 (9.3) | 19 (5.4) | 26 (19.1) | < 0.001 |
Substance Use History | ||||
Heavy Smoking (>1ppd) | 29 (6.4) | 19 (5.4) | 1 (0.7) | 0.034 |
Heavy Alcohol Use (> 10 drinks/week) | 30 (6.6) | 46 (13.0) | 5 (3.7) | < 0.001 |
Demographic Factors | ||||
Married | 192 (42.1) | 269 (76.2) | 105 (77.2) | < 0.001 |
College Completion | 165 (36.2) | 248 (70.3) | 46 (33.8) | < 0.001 |
Income < $30,000 | 161 (43.9) | 39 (12.0) | 42 (55.2) | < 0.001 |
Biopsy Outcomes | < 0.0013 | |||
Indolent Cancer | 167 (36.1) | 118 (33.2) | 38 (27.9) | 0.20 |
Clinically Significant Cancer | 175 (37.8) | 120 (33.8) | 26 (19.1) | < 0.001 |
No Cancer | 121 (26.1) | 117 (33.0) | 72 (52.9) | < 0.001 |