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Table 2 Characteristics of patients with and without sepsis

From: Presepsin and procalcitonin as predictors of sepsis based on the new Sepsis-3 definitions in obstructive acute pyelonephritis

Variables

Sepsis group

Non-sepsis group

P-value

n

%

n

%

Patients

  

11

 

50

  

Age (yr)

 

Median [IQR]

73 [55–77]

 

61 [52–76]

 

0.209

Gender

 

Male

3

27.3

21

42.0

 
 

Female

8

72.7

29

58.0

0.365

Performance status

 

0, 1

9

81.8

47

94.0

 
 

2, 3

2

18.2

3

6.0

0.182

Diabetes mellitus

 

Negative

8

72.7

37

74.0

 
 

Positive

3

27.3

13

26.0

0.931

Cardiovascular or neurologic disease

 

Negative

7

63.6

42

84.0

 
 

Positive

4

36.4

8

16.0

0.124

Immunocompromised status

 

Negative

10

90.9

48

96.0

 
 

Positive

1

9.1

2

4.0

0.480

CCI scores

 

0–2

8

72.7

47

94.0

 
 

≥3

3

27.3

3

6.0

0.066

Serum creatinine (mg/dL)

 

Median [IQR]

1.50 [1.22–2.14]

 

1.17 [0.78–1.70]

 

0.058

Leukocyte counts (×103/μL)

 

Median [IQR]

18.3 [10.0–22.3]

 

12.8 [10.1–15.5]

 

0.073

C-reactive protein (mg/dL)

 

Median [IQR]

14.17 [4.84–24.51]

 

10.72 [6.66–16.34]

 

0.586

Platelet counts (× 104/μL)

 

Median [IQR]

10.1 [6.1–14.8]

 

19.2 [15.5–26.9]

 

0.001

Serum albumin (g/dL)

 

Median [IQR]

3.0 [2.6–3.5]

 

3.6 [3.2–4.0]

 

0.016

PCT (ng/mL)

 

Median [IQR]

31.57 [1.83–134.40]

 

0.54 [0.14–4.86]

 

< 0.001

PSEP (pg/mL)

 

Median [IQR]

1080 [696–1550]

 

387 [313–558]

 

< 0.001

Midstream urine culture

 

Negative

0

0.0

7

14.0

 
 

Positive

11

100.0

43

86.0

0.187

Blood culture

 

Negative

1

9.1

38

76.0

 
 

Positive

10

90.9

12

24.0

< 0.001

Hydronephrosis

 

Low-grade

7

63.6

32

64.0

 
 

High-grade

4

36.4

18

36.0

0.982

Laterality of stone

 

Right

5

45.5

25

50.0

 
 

Left

6

54.5

25

50.0

0.785

Position of stone

 

Renal pelvis or PUJ

2

18.2

4

8.0

 
 

Upper ureter

6

54.5

29

58.0

 
 

Mid ureter

1

9.1

8

16.0

 
 

Lower ureter

2

18.2

9

18.0

0.738

Size of stone (mm)

Longest diameter

Median [IQR]

7.0 [5.0–12.0]

 

8.0 [6.0–10.0]

 

0.806

Shortest diameter

Median [IQR]

4.0 [3.0–8.0]

 

5.0 [4.0–7.0]

 

0.842

Drainage

 

Ureteral stent

10

90.9

46

92.0

 
 

Nephrostomy

1

9.1

4

8.0

0.905

  1. CCI Charlson Comorbidity Index, PCT Procalcitonin, PSEP Presepsin, PUJ Pelvic ureteral junction