Variable | Dimensions | Baseline differencea | Follow-up differencea | Treatment effectc | ||||||
---|---|---|---|---|---|---|---|---|---|---|
ORb/Coef. | SE | p-value | ORb/Coef. | SE | p-value | ORb/Coef. | SE | p-value | ||
EQ-5D-5L | Mobility | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No/slight problem | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Moderate/Severe/extreme problem | 1.33 | 0.92 | 0.675 | 0.57 | 0.45 | 0.481 | 0.32 | 0.33 | 0.267 | |
Selfcare | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
No/slight problem | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Moderate/Severe/extreme problem | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Usual activities | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
No/slight problem | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Moderate/Severe/extreme problem | 1.38 | 1.02 | 0.663 | 1.05 | 0.81 | 0.950 | 0.74 | 0.77 | 0.774 | |
Pain & discomfort | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
No/slight problem | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Moderate/Severe/extreme problem | 1.84 | 1.12 | 0.317 | 1.30 | 0.85 | 0.683 | 0.63 | 0.62 | 0.637 | |
Anxiety & depression | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
No/slight problem | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Moderate/Severe/extreme problem | 0.63 | 0.46 | 0.526 | 1.05 | 0.91 | 0.957 | 1.24 | 1.14 | 0.811 | |
Index | 0.02 | 0.05 | 0.643 | 0.04 | 0.05 | 0.471 | 0.02 | 0.03 | 0.540 | |
VAS | 7.27 | 6.35 | 0.258 | 5.54 | 4.66 | 0.240 | 3.82 | 4.51 | 0.402 | |
KHQ | Part I | Â | Â | Â | Â | Â | Â | Â | Â | Â |
General health perception (0-100) | 1.33 | 5.35 | 0.804 | -0.79 | 6.30 | 0.900 | -1.63 | 5.38 | 0.763 | |
Incontinence impact (0-100) | -11.11 | 6.44 | 0.091 | -3.50 | 6.79 | 0.609 | 3.07 | 6.26 | 0.626 | |
Part II | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Role limitations (0-100) | -13.19 | 6.66 | 0.054 | -10.53 | 6.71 | 0.123 | -1.06 | 4.96 | 0.831 | |
Physical limitations (0-100) | -7.75 | 6.17 | 0.216 | -9.75 | 6.76 | 0.156 | -3.82 | 4.96 | 0.446 | |
Social limitations (0-100) | -7.42 | 5.64 | 0.195 | -2.67 | 4.80 | 0.581 | 1.66 | 3.61 | 0.648 | |
Personal relationships (0-100) | -6.35 | 7.37 | 0.396 | -5.21 | 2.93 | 0.086 | -3.89 | 2.19 | 0.088 | |
Emotions (0-100) | -0.93 | 5.09 | 0.856 | -3.94 | 5.01 | 0.435 | -3.44 | 3.24 | 0.294 | |
Sleep/energy (0-100) | -9.83 | 8.67 | 0.263 | -10.25 | 8.90 | 0.255 | -3.68 | 6.92 | 0.598 | |
Severity measures (0-100) | -14.64 | 6.44 | 0.028 | -10.94 | 5.55 | 0.055 | -1.36 | 3.86 | 0.725 | |
Part III | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Symptom severity scale (0-30) | -1.92 | 1.21 | 0.119 | -2.67 | 0.93 | 0.006 | -1.77 | 0.76 | 0.025 | |
ICIQ-UI SF | Scale (0-21) | -1.06 | 1.18 | 0.374 | -2.39 | 1.01 | 0.022 | -1.87 | 0.84 | 0.031 |
GSE-UI | Scale (0-120) | 27.20 | 6.11 | 0.000 | 20.05 | 7.05 | 0.007 | -4.90 | 5.16 | 0.348 |
HADS | Anxiety scale (0-21) | -0.44 | 1.38 | 0.755 | -2.68 | 1.32 | 0.049 | -2.31 | 0.66 | 0.001 |
Normal | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Ill | 0.92 | 0.53 | 0.879 | 0.47 | 0.31 | 0.245 | 0.34 | 0.28 | 0.188 | |
Depression scale (0-21) | -0.21 | 1.05 | 0.840 | -0.36 | 1.03 | 0.732 | -0.17 | 0.46 | 0.715 | |
Normal | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
Ill | 2.30 | 2.11 | 0.364 | 1.05 | 0.91 | 0.957 | 0.44 | 0.54 | 0.505 |