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Table 3 Univariable and multivariable Cox proportional hazards regression analysis on the association between sociodemographic and clinical characteristics and mortality of the overall cohort

From: A comparison of stage-specific all-cause mortality between testicular sex cord stromal tumors and germ cell tumors: results from the National Cancer Database

  Univariable HR (95% CI) Multivariablea HR (95% CI) – Overall
Tumor type
 GCTs Ref. Ref.
 SCSTs 2.96 (2.03–4.33)*** 1.68 (1.13–2.49)*
Age (per 5-year increase) 1.21 (1.19–1.23)*** 1.18 (1.16–1.20)***
Race/ethnicity
 Non-Hispanic White Ref. Ref.
 Non-Hispanic Black 1.80 (1.41–2.29)*** 1.13 (0.89–1.45)
 Hispanic/other 1.27 (1.13–1.43)*** 1.14 (1.01–1.30)*
Insurance
 Private insurance Ref. Ref.
 Uninsured 2.63 (2.29–3.01)*** 2.32 (2.01–2.66)***
 Medicaid/Medicare/other government insurance 4.33 (3.88–4.83)*** 2.72 (2.42–3.05)***
Income (per year)
  < $38,000 Ref. Ref.
 $38,000–$62,999 0.71 (0.62–0.81)*** 0.94 (0.82–1.09)
  > $63,000 0.44 (0.38–0.50)*** 0.76 (0.63–0.92)**
Percent in ZIP code without a high school diploma
  > 21% Ref. Ref.
 7–20.9% 0.63 (0.56–0.71)*** 0.83 (0.73–0.96)*
  < 7% 0.43 (0.37–0.49)*** 0.74 (0.61–0.90)**
Residence
 Metropolitan Ref. Ref.
 Urban/rural 1.49 (1.33–1.67)*** 1.13 (1.00–1.28)
Charlson-Deyo comorbidity score
 0 Ref. Ref.
  ≥ 1 3.23 (2.82–3.70)*** 2.06 (1.79–2.37)***
  1. CI Confidence interval, GCTs Germ cell tumors, HR Hazard ratio, IQR Interquartile range, SCSTs Sex cord stromal tumors
  2. *p < 0.05
  3. **p < 0.01
  4. ***p < 0.001
  5. aThe following variables were included in the multivariable analysis: tumor type, age, diagnosis year, race/ethnicity, insurance, yearly income, percent in ZIP code without a high school diploma, residence, Charlson-Deyo comorbidity score