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Table 3 Univariable and multivariable Cox proportional hazards regression analysis on the association between sociodemographic and clinical characteristics and mortality of the overall cohort

From: A comparison of stage-specific all-cause mortality between testicular sex cord stromal tumors and germ cell tumors: results from the National Cancer Database

 

Univariable HR (95% CI)

Multivariablea HR (95% CI) – Overall

Tumor type

 GCTs

Ref.

Ref.

 SCSTs

2.96 (2.03–4.33)***

1.68 (1.13–2.49)*

Age (per 5-year increase)

1.21 (1.19–1.23)***

1.18 (1.16–1.20)***

Race/ethnicity

 Non-Hispanic White

Ref.

Ref.

 Non-Hispanic Black

1.80 (1.41–2.29)***

1.13 (0.89–1.45)

 Hispanic/other

1.27 (1.13–1.43)***

1.14 (1.01–1.30)*

Insurance

 Private insurance

Ref.

Ref.

 Uninsured

2.63 (2.29–3.01)***

2.32 (2.01–2.66)***

 Medicaid/Medicare/other government insurance

4.33 (3.88–4.83)***

2.72 (2.42–3.05)***

Income (per year)

  < $38,000

Ref.

Ref.

 $38,000–$62,999

0.71 (0.62–0.81)***

0.94 (0.82–1.09)

  > $63,000

0.44 (0.38–0.50)***

0.76 (0.63–0.92)**

Percent in ZIP code without a high school diploma

  > 21%

Ref.

Ref.

 7–20.9%

0.63 (0.56–0.71)***

0.83 (0.73–0.96)*

  < 7%

0.43 (0.37–0.49)***

0.74 (0.61–0.90)**

Residence

 Metropolitan

Ref.

Ref.

 Urban/rural

1.49 (1.33–1.67)***

1.13 (1.00–1.28)

Charlson-Deyo comorbidity score

 0

Ref.

Ref.

  ≥ 1

3.23 (2.82–3.70)***

2.06 (1.79–2.37)***

  1. CI Confidence interval, GCTs Germ cell tumors, HR Hazard ratio, IQR Interquartile range, SCSTs Sex cord stromal tumors
  2. *p < 0.05
  3. **p < 0.01
  4. ***p < 0.001
  5. aThe following variables were included in the multivariable analysis: tumor type, age, diagnosis year, race/ethnicity, insurance, yearly income, percent in ZIP code without a high school diploma, residence, Charlson-Deyo comorbidity score