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Table 1 U&LP changes in the amplitude of phasic contractions in response to the five primary prostaglandin agonists (mean ± SEM)

From: The five primary prostaglandins stimulate contractions and phasic activity of the urinary bladder urothelium, lamina propria and detrusor

 

1 μM of agonist

 

10 μM of agonist

 

Agonist

Absence (g)

Presence (g)

n

Absence (g)

Presence (g)

n

PGE2

0.53 ± 0.05

0.40 ± 0.03***

38

0.53 ± 0.04

0.37 ± 0.03**

42

PGF2α

0.30 ± 0.03

0.29 ± 0.01

10

0.51 ± 0.06

0.46 ± 0.08

14

TXA2

0.90 ± 0.16

0.62 ± 0.14**

8

0.75 ± 0.16

0.71 ± 0.25

6

PGD2

0.59 ± 0.10

0.46 ± 0.04

4

0.55 ± 0.08

0.43 ± 0.06

8

PGI2

0.64 ± 0.07

0.56 ± 0.07

8

0.57 ± 0.09

0.43 ± 0.06*

8

  1. *p < 0.05, **p < 0.01, ***p < 0.001. Paired Student’s t-test
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BMC Urology

ISSN: 1471-2490

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