Fig. 1

Gene expression analysis. Analysis of the relative expression of five different genes was performed by quantification of real-time one-step RT-PCR using the Mx3000P (Agilent) tool in tissue samples of the BPH group (n = 12), primary PCa group (n = 13), ADT ≤12 months group (n = 4) and ADT > 12 months group (n = 6). The included AR (a), AKR1C3 (b), SRD5A1 (c), SRD5A2 (d), and SRD5A3 (e). Statistical analysis was performed by using the Mann-Whitney test, comparing each group to another in a paired manner. * p < 0.05 and ** p < 0.01. Standard errors of the means are indicated by bars. a-e All experiments were performed at least two times